Question · asked by 1 review

Summary of findings table ‐ Ondansetron vs placebo: Risk for at least one adverse event per patient

Population
patients with chronic kidney disease (CKD) pruritus
Intervention
Summary of findings table ‐ Ondansetron
Comparison
placebo
Outcome
Risk for at least one adverse event per patient

It is very uncertain whether summary of findings table ‐ Ondansetron changes risk for at least one adverse event per patient compared with placebo (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Summary of findings table ‐ Ondansetron vs placebo
Risk for at least one adverse event per patient · patients with chronic kidney disease (CKD) pruritus
It is very uncertain whether summary of findings table ‐ Ondansetron changes risk for at least one adverse event per patient compared with placebo (very low certainty).
Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane Headline outcomes only
RR 2.54 [0.38, 16.78]3 studies · 174 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pharmacological interventions for pruritus in adult palliative care patients
2024 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.