Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

493 questions · 509 findings · 56 reviews · Headline outcomes only

No studies found 149 · 29.3%GRADE not reported 9 · 1.8%Very low 128 · 25.1%Low 123 · 24.2%Moderate 79 · 15.5%High 21 · 4.1%

Medical or surgical intervention, or both, for gastro‐oesophageal reflux disease vs nil intervention, delayed intervention control, or placebo

Exacerbations: number of people experiencing moderate or severe exacerbations · treatment for asthma in adults and children with asthma and GORD

Medical or surgical intervention, or both, for gastro‐oesophageal… showed no clear difference in number of participants with moderate/severe acute exacerbations… compared with nil intervention, delayed intervention control, or placebo (low certainty).

1 finding from 1 review

Medical or surgical intervention, or both, for gastro‐oesophageal reflux disease vs nil intervention, delayed intervention control, or placebo

Lung function: FEV1 mL (change from baseline) · treatment for asthma in adults and children with asthma and GORD
1 finding from 1 review

Medical or surgical intervention, or both, for gastro‐oesophageal reflux disease vs nil intervention, delayed intervention control, or placebo

Use of "rescue" medications and emergency action plans: B2 use puffs per day Duration of treatment: range 14 weeks to 24 weeks · treatment for asthma in adults and children with asthma and GORD
1 finding from 1 review

Therapeutic swallowing exercises vs treatment

Adverse event: Weight change Patient's body weight 6 months before the start of treatment was retrieved from the patient's medical notes and "relative weight change" was calculated as the percentage weight change relative to the weight at week 0 6... · adults with advanced head and neck cancer

It is very uncertain whether therapeutic swallowing exercises changes adverse event: Weight change Patient's body weight 6 months before… compared with treatment (very low certainty).

1 finding from 1 review

GnRHa treatment vs placebo or no pretreatment

Operating time · women with uterine fibroids
3 findings from 1 review

GnRHa treatment vs placebo or no pretreatment

Intraoperative blood loss (mL) · women with uterine fibroids
3 findings from 1 review

GnRHa treatment vs placebo or no pretreatment

Blood transfusion · women with uterine fibroids

GnRHa treatment showed no clear difference in blood transfusions compared with no pretreatment or placebo before myomectomy (operative and… (low certainty).

3 findings from 1 review

GnRHa treatment vs placebo or no pretreatment

Overall postoperative morbidity · women with uterine fibroids

GnRHa treatment showed no clear difference in postoperative morbidity compared with no pretreatment or placebo before myomectomy (operative and… (low certainty).

3 findings from 1 review