GnRHa treatment vs placebo or no pretreatment: Overall postoperative morbidity
GnRHa treatment showed no clear difference in postoperative morbidity compared with no pretreatment or placebo before myomectomy (operative and… (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
GnRHa treatment vs no pretreatment or placebo before myomectomy (operative and postoperative outcomes Postoperative morbidity · women with uterine fibroids GnRHa treatment showed no clear difference in postoperative morbidity compared with no pretreatment or placebo before myomectomy (operative and… (low certainty). Preoperative medical therapy before surgery for uterine fibroids (2017) · Cochrane Headline outcomes only | OR 1.07 [0.43, 2.64] | 5 studies · 190 participants | Low |
GnRHa treatment vs no pretreatment or placebo before resection Postoperative morbidity · women with uterine fibroids The review found no eligible studies for this question. Preoperative medical therapy before surgery for uterine fibroids (2017) · Cochrane Headline outcomes only | no estimate extracted | Not reported | No studies found |
GnRHa treatment vs no pretreatment or placebo before hysterectomy (operative and postoperative outcomes Postoperative morbidity · women with uterine fibroids GnRHa treatment may leads to lower postoperative morbidity compared with no pretreatment or placebo before hysterectomy (operative and… (low certainty). Preoperative medical therapy before surgery for uterine fibroids (2017) · Cochrane Headline outcomes only | OR 0.54 [0.32, 0.91] | 7 studies · 772 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.