Cochrane · systematic review · CD013692
Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis
Xu, R, Zhang, X, Liu, S, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
2
Included studies
NR
No studies 2 · 28.6%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 28.6%Moderate 3 · 42.9%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Endovascular treat ment plus medical treatment compared to medical treatment alone for vertebral artery stenosis
Population: people with vertebral artery stenosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
30‐day post‐randomisation death/stroke Endovascular treat ment plus medical treatment vs medical treatment alone | RR 2.33 [0.77, 7.07] | 3 studies · 349 participants | Low Downgraded: risk of bias, imprecision |
Fatal/non‐fatal stroke in the territory of the treated vertebral artery stenosis(assessed after 30 days post‐randomisation to completion of Endovascular treat ment plus medical treatment vs medical treatment alone | RR 0.51 [0.26, 1.01] | 3 studies · 349 participants | Moderate Downgraded: risk of bias, imprecision |
Stroke (ischaemic or haemorrhagic)Median Endovascular treat ment plus medical treatment vs medical treatment alone | RR 0.77 [0.44, 1.32] | 3 studies · 349 participants | Moderate Downgraded: risk of bias, imprecision |
DeathMedian Endovascular treat ment plus medical treatment vs medical treatment alone | RR 0.78 [0.37, 1.62] | 3 studies · 349 participants | Low Downgraded: risk of bias, imprecision |
Stroke or TIAMedian Endovascular treat ment plus medical treatment vs medical treatment alone | RR 0.65 [0.39, 1.06] | 2 studies · 234 participants | Moderate Downgraded: risk of bias, imprecision |
Restenosis ‐ not measured Endovascular treat ment plus medical treatment vs medical treatment alone | no estimate extracted | NR | No studies |
Good functional outcome ‐ not measured Endovascular treat ment plus medical treatment vs medical treatment alone | no estimate extracted | NR | No studies |