Question · asked by 1 review

GnRHa treatment vs placebo or no pretreatment: Blood transfusion

GnRHa treatment showed no clear difference in blood transfusions compared with no pretreatment or placebo before myomectomy (operative and… (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
GnRHa treatment vs no pretreatment or placebo before myomectomy (operative and postoperative outcomes
Blood transfusions · women with uterine fibroids
GnRHa treatment showed no clear difference in blood transfusions compared with no pretreatment or placebo before myomectomy (operative and… (low certainty).
Preoperative medical therapy before surgery for uterine fibroids (2017) · Cochrane Headline outcomes only
OR 0.85 [0.26, 2.75]4 studies · 121 participantsLow
GnRHa treatment vs no pretreatment or placebo before resection
Blood transfusions · women with uterine fibroids
The review found no eligible studies for this question.
Preoperative medical therapy before surgery for uterine fibroids (2017) · Cochrane Headline outcomes only
no estimate extractedNot reportedNo studies found
GnRHa treatment vs no pretreatment or placebo before hysterectomy (operative and postoperative outcomes
Blood transfusions · women with uterine fibroids
GnRHa treatment showed no clear difference in blood transfusions compared with no pretreatment or placebo before hysterectomy (operative and… (moderate certainty).
Preoperative medical therapy before surgery for uterine fibroids (2017) · Cochrane Headline outcomes only
OR 0.54 [0.29, 1.01]6 studies · 601 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Preoperative medical therapy before surgery for uterine fibroids
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.