Caries incidence rate per person-year at risk (D3) · Children and adolescents with permanent dentition
Adjusted for groups 1-4 including relevance of evidence and risk of bias meta-regression beta was -0.02 per additional follow-up year.
5 findings from 1 review
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for groups 1-4 including relevance of evidence and risk of bias
Meta-regression beta per year of follow-up -0.02 [-0.05, 0.01]
15 studies · 10768 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for bitewings age at baseline and baseline caries experience
Meta-regression beta per year of follow-up 0.00 [-0.00, 0.01]
15 studies · 10768 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for bitewings and age at baseline
Meta-regression beta per year of follow-up 0.00 [-0.00, 0.01]
15 studies · 10768 participants
GRADE not reported
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Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for groups 1-3 including decade and preventive intervention
Meta-regression beta per year of follow-up -0.00 [-0.02, 0.02]
15 studies · 10768 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Not adjusted
Meta-regression beta per year of follow-up -0.00 [-0.01, 0.01]
15 studies · 10768 participants
GRADE not reported
Caries experience (mean DMFT) · 12-year-old children across European countries (national/regional epidemiological surveys, 2011-2022)
Mean DMFT tended to increase with unemployment rate (low 1.23, medium 2.08, high 2.38; ANOVA p<.05); descriptive country-level means only, not meta-analyzed or GRADE-rated.
3 findings from 1 review
Odds of higher caries (DMFT) category · 12-year-old children across European countries (national/regional epidemiological surveys, 2011-2022)
Unemployment rate was not independently associated with DMFT category in the adjusted model (OR 0.99, 95% CI 0.44 to 2.23); not GRADE-rated.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Low-level laser therapy (LLLT) showed no clear difference in radiological failure compared with low-level laser therapy (LLLT) + calcium hydroxide; GRADE not reported.
1 finding from 1 review
Reduction in level of contamination in aerosols (CFU per cubic feet/min/patient) using Reyniers slit sampler 30 inches (76 cm) from floor · People undergoing aerosol-generating procedures (AGPs) in a dental setting
It is very uncertain whether laminar air flow with HEPA filter changes reduction in level of contamination in aerosols (CFU per cubic… compared with without laminar flow or filter (very low certainty).
1 finding from 1 review
Reduction in level of contamination in aerosols (CFU per cubic feet/min/patient) using Andersen cascade sampler 20-30 cm from mouth · People undergoing aerosol-generating procedures (AGPs) in a dental setting
It is very uncertain whether laminar air flow with HEPA filter changes reduction in level of contamination in aerosols (CFU per cubic… compared with without laminar flow or filter (very low certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure
In the high-risk-study-excluded sensitivity meta-regression, longer follow-up was associated with lower success.
1 finding from 1 review
Stability of crossbite correction (relapse of canine expansion) · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
1 finding from 1 review
Canine expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
1 finding from 1 review
Stability of crossbite correction (relapse of molar expansion) · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
1 finding from 1 review
Molar expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
1 finding from 1 review
Salivary cortisol, cariogenic bacterial load and dental caries · Kindergarten-age children
In one cross-sectional study of children, low socioeconomic status, higher basal salivary cortisol and higher cariogenic bacterial counts were each independently associated with higher dental caries risk; not pooled (ungraded).
1 finding from 1 review
Incidence of ORN · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
It is very uncertain whether hyperbaric oxygen therapy (HBO) following extractions changes incidence of ORN compared with perioperative antibiotic prophylaxis (penicillin G) following… (very low certainty).
1 finding from 1 review
Adverse effects · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
1 finding from 1 review
Adverse effects were an outcome of interest in the study conducting this comparison, however no mention was made of the presence or absence of any adverse events
1 study · 74 participants
Very low
Dental caries in children · Mother-child pairs
In one cross-sectional study, higher maternal allostatic load was associated with child dental caries experience and with health-related maternal care-taking behaviours; not pooled (ungraded).
1 finding from 1 review
Caries experience (mean DMFT) · Adults aged 19-60 years
Populations with a higher proportion of people with low socioeconomic status had higher caries experience (pooled DMFT 15.99 vs 5.50), and meta-regression associated low SES with higher DMFT (about 10.35 more DMFT per unit; p=0.050); ungraded observational evidence.
5 findings from 1 review
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Annual decline in percentage of caries-free participants (permanent dentition, D3) · Children and adolescents (permanent dentition, D3, up to 21 y), Western or comparable populations
For low baseline caries experience, the annual decline in caries-free participants ranged 4.3% to 10.2% (9 studies; ungraded).
4 findings from 1 review
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesAnnual (studies with >=3 y follow-up) · Western Europe, North America, Australia, New Zealand (or comparable Western populations) · Baseline caries experience: low
4.3% to 10.2%
9 studies · 4811 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesAnnual (studies with >=3 y follow-up) · Western Europe, North America, Australia, New Zealand (or comparable Western populations)
0.8% to 10.2%
18 studies · 12017 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesAnnual (studies with >=3 y follow-up) · Western Europe, North America, Australia, New Zealand (or comparable Western populations) · Baseline caries experience: high
0.8% to 2.2%
2 studies · 5029 participants
GRADE not reported
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Annual increment in DMFT (permanent dentition) · Children and adolescents (permanent dentition, D3, up to 21 y), Western or comparable populations
In the permanent dentition, the annual DMFT increment ranged from 0.06 to 0.73 across 14 studies, and was higher where baseline caries experience was higher (descriptive range; ungraded).
4 findings from 1 review
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Caries development in permanent teeth · Children and adolescents (permanent dentition, D3, up to 21 y), Western or comparable populations
In the permanent dentition, the annual DMFS increment ranged from 0.07 to 1.77 across 26 studies, and was higher where baseline caries experience was higher (descriptive range; ungraded).
4 findings from 1 review
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