Change in Mutans streptococci (MS) count in dental plaque · healthy people
Xylitol reduced Mutans streptococci in dental plaque more than sorbitol (SMD -0.45, 95% CI -0.69 to -0.21; 4 trials, I2=7%); not GRADE-rated.
1 finding from 1 review
Caries increment in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)
Evidence on the association between sociodemographic/socioeconomic factors and permanent-teeth caries is weak and inconsistent (3 studies; could not be pooled; not GRADE-rated).
1 finding from 1 review
Caries development in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)
Early-childhood oral hygiene and dietary habits show inconsistent associations with permanent-teeth caries, often losing significance after adjustment for past caries (2 studies; not pooled; not GRADE-rated).
1 finding from 1 review
Projected mean DMFT (children below 5 years) · Alaska Native children (below age 18)
A simulation projected mean DMFT in children under 5 would fall from 7.4 to 4.9 under the PDHA model (certainty not graded).
1 finding from 1 review
Early childhood caries (ECC) · Children aged 6 years or younger (preschool children)
Adjusted analyses also showed no association between low birth weight and early childhood caries (adjusted OR 1.05, 95% CI 0.71 to 1.57); certainty not graded.
3 findings from 1 review
Prevalence of untreated decay (% DT > 0) · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States
In Australia, low versus high income differed by 11.90 percentage points in prevalence of untreated decay.
5 findings from 1 review
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Mean number of decayed teeth (mean DT) · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States
Across four countries, low versus high income differed by 0.44 decayed teeth in mean number of decayed teeth (random-effects meta-analysis; I2=76.4%).
5 findings from 1 review
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Prevalence of fair/poor self-rated oral health · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States
Across four countries, low versus high income differed by 15.77 percentage points in prevalence of fair/poor self-rated oral health (random-effects meta-analysis; I2=13.4%).
5 findings from 1 review
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Marginal adaptation (clinically detectable deterioration) · People with permanent posterior teeth restored with class I or II direct restorations
At 60 months, marginal adaptation did not differ significantly between the composites (4 groups; ungraded).
5 findings from 1 review
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Secondary caries · People with permanent posterior teeth restored with class I or II direct restorations
No secondary caries was reported at 24 months in any of seven studies, so no meta-analysis was possible (ungraded).
2 findings from 1 review
Marginal discoloration · People with permanent posterior teeth restored with class I or II direct restorations
At 24 months, marginal discoloration did not differ significantly (7 groups; p = 0.77; ungraded).
4 findings from 1 review
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Retention (restoration loss) · People with permanent posterior teeth restored with class I or II direct restorations
At 24 months, retention did not differ significantly between the composites (6 studies; ungraded).
2 findings from 1 review
Postoperative sensitivity · People with permanent posterior teeth restored with class I or II direct restorations
Postoperative sensitivity at 12 months did not differ significantly between low polymerization shrinkage and methacrylate composites (OR 1.65, 95% CI 0.71 to 3.81; Moderate certainty).
2 findings from 1 review
Determinants of oral diseases · Adult residents of slums and non-slum urban settings of LMICs
Age, education, income, oral-hygiene behaviour, dental-visit pattern and slum/disadvantaged residence are associated with oral disease; gender effects are disease-specific; ungraded.
1 finding from 1 review
Fourteen studies reported determinants: older age, less education, lower income, poor oral hygiene behaviour (brushing frequency, technique), infrequent dental visits and disadvantaged/slum residential setting were…
14 studies
GRADE not reported
Salivary flow rate · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth
Across 19 studies the effect of gum chewing on stimulated and/or unstimulated salivary flow rate was mixed (9 positive, 10 no effect); this broad outcome was not meta-analyzed.
1 finding from 1 review
The effect of gum chewing on xerostomia and salivary flow rate in elderly and medically compromised subjects: a… 2023 All outcomesVarious (single session to 12 months) · Haemodialysis units, elderly / geriatric care, cancer and palliative care, and xerostomia / hyposalivation clinics (studies from multiple countries)
Narrative vote-count: of 19 studies measuring stimulated and/or unstimulated saliva flow rate, 9 found a positive effect of gum chewing [17,18,22,24,27,35,36,38,39] and 10 detected no effect…
19 studies
GRADE not reported
Salivary flow rate (unstimulated) · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth
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1 finding from 1 review
Salivary flow rate (unstimulated) · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth
In elderly and medically compromised people with xerostomia, chewing sugar-free gum daily for two or more weeks produces a small but statistically significant increase in unstimulated whole salivary flow rate versus no gum (SMD 0.44, 95% CI 0.22 to 0.66); certainty of evidence was not formally graded.
1 finding from 1 review
Severe early childhood caries · Children aged 5-6 years in Ajman schools
Low family income was associated with higher odds of severe early childhood caries.
1 finding from 1 review
Oral health-related quality of life · people aged 60 years and older living in the community
No statistically significant difference in OHRQoL was reported by edentulism prevalence.
1 finding from 1 review
MMP-9 location/depth · Human carious dentin
Opposite effect directions were reported for MMP-9 by lesion depth or location (very low certainty).
1 finding from 1 review
no estimate extracted
3 studies
Very low