Findings

What do systematic reviews say?

72 questions · 85 findings · 13 reviews · Pain, Palliative and Supportive Care

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No studies found 11 · 12.9%GRADE not reported 0 · 0%Very low 32 · 37.6%Low 33 · 38.8%Moderate 9 · 10.6%High 0 · 0%

Consumption of intravenous morphine equivalents (mg): PCA vs non‐patient controlled opioid analgesia

Consumption of morphine equivalents 0 to 24 hmg · patients with postoperative pain

1 finding from 1 review

Patient controlled opioid analgesia versus non‐patient controlled opioid analgesia for postoperative pain 2015 · Cochrane Headline outcomes only
no estimate extracted
25 studies · 1586 participants
Low

Consumption of intravenous morphine equivalents (mg): PCA vs non‐patient controlled opioid analgesia

Consumption of morphine equivalents 25 to 48 hmg · patients with postoperative pain

1 finding from 1 review

Patient controlled opioid analgesia versus non‐patient controlled opioid analgesia for postoperative pain 2015 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 449 participants
Moderate

Consumption of intravenous morphine equivalents (mg): PCA vs non‐patient controlled opioid analgesia

Consumption of morphine equivalents 0 to 48 hmg · patients with postoperative pain

1 finding from 1 review

Patient controlled opioid analgesia versus non‐patient controlled opioid analgesia for postoperative pain 2015 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 334 participants
Very low

Consumption of intravenous morphine equivalents (mg): PCA vs non‐patient controlled opioid analgesia

Consumption of morphine equivalents 0 to 72 hmg · patients with postoperative pain

1 finding from 1 review

Patient controlled opioid analgesia versus non‐patient controlled opioid analgesia for postoperative pain 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 244 participants
Very low

Intervention not reported

Pain intensity VAS score 1 mg morphine vs 2 mg morphine0‐10 cm VAS score. Scale from: 0 to 10. · patients undergoing knee arthroscopy

1 finding from 1 review

Single dose intra‐articular morphine for pain control after knee arthroscopy 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 105 participants
Low

Intervention not reported

Pain intensity VAS score1 mg morphine vs 2 mg morphine 0‐10 cm VAS score. Scale from: 0 to 10. · patients undergoing knee arthroscopy

1 finding from 1 review

Single dose intra‐articular morphine for pain control after knee arthroscopy 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 105 participants
Low

Intervention not reported

Pain intensity VAS score1 mg morphine vs 2 mg morphine 0‐10 cm VAS score. Scale from: 0 to 10. · patients undergoing knee arthroscopy

1 finding from 1 review

Single dose intra‐articular morphine for pain control after knee arthroscopy 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 45 participants
Low

Intervention not reported

Analgesia duration 1 mg morphine vs 2 mg morphineTime duration from the end of surgery to the time of first analgesic consumption · patients undergoing knee arthroscopy

1 finding from 1 review

Single dose intra‐articular morphine for pain control after knee arthroscopy 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Moderate

Intervention not reported

Adverse events 1 mg morphine vs 2 mg morphinePercentage of participants with any adverse event · patients undergoing knee arthroscopy

The review found no eligible studies for this question.

1 finding from 1 review

Single dose intra‐articular morphine for pain control after knee arthroscopy 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Pain intensity VAS score1 mg morphine vs 4 mg/5 mg morphine 0‐10 cm VAS score. Scale from: 0 to 10. · patients undergoing knee arthroscopy

1 finding from 1 review

Single dose intra‐articular morphine for pain control after knee arthroscopy 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 67 participants
Low

Intervention not reported

Pain intensity VAS score1 mg morphine vs 4 mg/5 mg morphine 0‐10 cm VAS score. Scale from: 0 to 10. · patients undergoing knee arthroscopy

1 finding from 1 review

Single dose intra‐articular morphine for pain control after knee arthroscopy 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 67 participants
Low

Intervention not reported

Pain intensity VAS score1 mg morphine vs 4 mg/5 mg morphine 0‐10 cm VAS score. Scale from: 0 to 10. · patients undergoing knee arthroscopy

1 finding from 1 review

Single dose intra‐articular morphine for pain control after knee arthroscopy 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 67 participants
Low

Intervention not reported

Analgesia duration 1 mg morphine vs 4 mg/5 mg morphinetime duration from the end of surgery to the first time of analgesic consumption · patients undergoing knee arthroscopy

1 finding from 1 review

Single dose intra‐articular morphine for pain control after knee arthroscopy 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Moderate

Intervention not reported

Adverse events 1 mg morphine vs 4 mg/5 mg morphinePercentage of participants with any adverse event · patients undergoing knee arthroscopy

The review found no eligible studies for this question.

1 finding from 1 review

Single dose intra‐articular morphine for pain control after knee arthroscopy 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cannabis‐based medicines vs placebo medication

Daily maintenance opioid dosage (mg morphine equivalent) · adults with cancer‐related pain

Cannabis‐based medicines showed no clear difference in daily maintenance opioid dosage (mg morphine equivalent) compared with placebo medication (low certainty).

1 finding from 1 review

Cannabis‐based medicines and medical cannabis for adults with cancer pain 2023 · Cochrane Headline outcomes only
SMD 0.08
3 studies · 970 participants
Low

Cannabis‐based medicines vs placebo medication

Daily breakthrough opioid dosage (mg morphine equivalent) · adults with cancer‐related pain

Cannabis‐based medicines showed no clear difference in daily breakthrough opioid dosage (mg morphine equivalent) compared with placebo medication (moderate certainty).

1 finding from 1 review

Cannabis‐based medicines and medical cannabis for adults with cancer pain 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 957 participants
Moderate

Perioperative intravenous ketamine vs placebo

Consumption of morphine equivalents 0 to 72 hmg · adults undergoing surgery

1 finding from 1 review

Perioperative intravenous ketamine for acute postoperative pain in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
65 studies · 4004 participants
Moderate

Ketorolac vs placebo

Opioid consumption (mg IV morphine equivalents): PACU · children with acute postoperative pain

1 finding from 1 review

Ketorolac for postoperative pain in children 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 162 participants
Very low

Ketorolac vs placebo

Opioid consumption (mg IV morphine equivalents): 0 to 4 h · children with acute postoperative pain

1 finding from 1 review

Ketorolac for postoperative pain in children 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 129 participants
Very low

Ibuprofen vs morphine

Relief of pain · children with acute postoperative pain

The review found no eligible studies for this question.

2 findings from 1 review

Ibuprofen for acute postoperative pain in children 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Ibuprofen for acute postoperative pain in children 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found