Question · asked by 1 review
Cannabis‐based medicines vs placebo medication: Daily breakthrough opioid dosage (mg morphine equivalent)
- Population
- adults with cancer‐related pain
- Intervention
- Cannabis‐based medicines
- Comparison
- placebo medication
- Outcome
- Daily breakthrough opioid dosage (mg morphine equivalent)
Cannabis‐based medicines showed no clear difference in daily breakthrough opioid dosage (mg morphine equivalent) compared with placebo medication (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Cannabis‐based medicines vs placebo medication Daily breakthrough opioid dosage (mg morphine equivalent) · adults with cancer pain Cannabis‐based medicines showed no clear difference in daily breakthrough opioid dosage (mg morphine equivalent) compared with placebo medication (moderate certainty). Cannabis‐based medicines and medical cannabis for adults with cancer pain (2023) · Cochrane Headline outcomes only | no estimate extracted | 3 studies · 957 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Cannabis‐based medicines and medical cannabis for adults with cancer pain 2023 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.