PAR score · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase) with headgear showed no clear difference in PAR score compared with late treatment (one-phase in adolescence) with headgear; GRADE not reported.
1 finding from 1 review
Incidence of new incisal trauma · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase) with headgear may leads to lower incidence of new incisal trauma compared with late treatment (one-phase in adolescence) with headgear (low certainty).
1 finding from 1 review
Final overjet · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase) with headgear showed no clear difference in final overjet compared with late treatment (one-phase in adolescence) with headgear (low certainty).
2 findings from 1 review
Incidence of incisal trauma · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase) with headgear showed no clear difference in incidence of incisal trauma compared with late treatment (one-phase in adolescence) with headgear; GRADE not reported.
1 finding from 1 review
Final ANB · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase) with headgear led to lower final ANB compared with late treatment (one-phase in adolescence) with headgear; GRADE not reported.
2 findings from 1 review
Self concept · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase: phase 1 in childhood, phase 2 in… showed no clear difference in self concept compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.
2 findings from 1 review
Incidence of new incisal trauma · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase: phase 1 in childhood, phase 2 in… probably leads to lower incidence of new incisal trauma compared with late treatment (one-phase in adolescence) with functional appliance (moderate certainty).
1 finding from 1 review
Final overjet · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase: phase 1 in childhood, phase 2 in… led to lower final overjet compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.
2 findings from 1 review
Final ANB · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase: phase 1 in childhood, phase 2 in… led to lower final ANB compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.
2 findings from 1 review
Incidence of incisal trauma · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase: phase 1 in childhood, phase 2 in… showed no clear difference in incidence of incisal trauma compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.
1 finding from 1 review
PAR score · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase: phase 1 in childhood, phase 2 in… led to lower PAR score compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.
2 findings from 1 review
MD -10.52 [-12.32, -8.71]
2 studies · 349 participants
GRADE not reported
MD 0.62 [-0.66, 1.91]
3 studies · 360 participants
GRADE not reported
Use of conventional phototherapy, if sunlight (with or without filters or amplification) was first used for prevention or early treatmentc · term and late preterm neonates
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Acceptability of treatment ‐ leaving the study early · schizophrenia
Maintenance treatment with antipsychotic drugs leads to lower leaving the study early: due to any reason (acceptability of… compared with placebo/no treatment (high certainty).
1 finding from 1 review
Satisfaction with treatment: leaving the study early Endpoint data (events) · people in the prodromal stage of psychosis
It is very uncertain whether group C other: integrated treatment changes satisfaction with treatment: leaving the study early Endpoint data… compared with standard treatment (very low certainty).
1 finding from 1 review
Use of conventional phototherapy, if sunlight (with or without filters or amplification) was first used for prevention or early treatmentc · infants with confirmed hyperbilirubinemia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Failure of treatment ‐ death or intermittent positive‐pressure ventilation (IPPV) before hospital discharge · preterm infants with respiratory distress for initial respiratory support
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Acceptability ‐ total dropouts · schizophrenia
Lithium as sole treatment showed no clear difference in acceptability of treatment leaving early due to any reason compared with placebo (low certainty).
1 finding from 1 review
Satisfaction with treatment: leaving the study early FACT Long‐term · people in the prodromal stage of psychosis
It is very uncertain whether group C other: family treatment changes satisfaction with treatment: leaving the study early FACT Long‐term compared with enhanced care (very low certainty).
1 finding from 1 review
Unacceptability of treatment (drop-outs / leaving study early) · patients with schizophrenia
It is very uncertain whether BENZODIAZEPINES AS SOLE TREATMENT changes leaving the study early due to any reason (overall acceptability of… compared with PLACEBO (very low certainty).
1 finding from 1 review
Adverse effects (drop‐outs due to adverse effects4) · patients with schizophrenia
1 finding from 1 review