Question · asked by 1 review

Maintenance treatment with antipsychotic drugs vs placebo/no treatment: Acceptability of treatment ‐ leaving the study early

Population
schizophrenia
Intervention
Maintenance treatment with antipsychotic drugs
Comparison
placebo/no treatment
Outcome
Acceptability of treatment ‐ leaving the study early

Maintenance treatment with antipsychotic drugs leads to lower leaving the study early: due to any reason (acceptability of… compared with placebo/no treatment (high certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Maintenance treatment with antipsychotic drugs vs placebo/no treatment
Leaving the study early: due to any reason (acceptability of treatment) · schizophrenia
Maintenance treatment with antipsychotic drugs leads to lower leaving the study early: due to any reason (acceptability of… compared with placebo/no treatment (high certainty).
Maintenance treatment with antipsychotic drugs for schizophrenia (2020) · Cochrane Headline outcomes only
RR 0.54 [0.49, 0.61]56 studies · 7001 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Maintenance treatment with antipsychotic drugs for schizophrenia
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.