Question · asked by 1 review

BENZODIAZEPINES AS SOLE TREATMENT vs placebo: Unacceptability of treatment (drop-outs / leaving study early)

Population
patients with schizophrenia
Intervention
BENZODIAZEPINES AS SOLE TREATMENT
Comparison
placebo
Outcome
Unacceptability of treatment (drop-outs / leaving study early)

It is very uncertain whether BENZODIAZEPINES AS SOLE TREATMENT changes leaving the study early due to any reason (overall acceptability of… compared with PLACEBO (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
BENZODIAZEPINES AS SOLE TREATMENT vs PLACEBO
Leaving the study early due to any reason (overall acceptability of treatment) · people with schizophrenia
It is very uncertain whether BENZODIAZEPINES AS SOLE TREATMENT changes leaving the study early due to any reason (overall acceptability of… compared with PLACEBO (very low certainty).
Benzodiazepines for schizophrenia (2012) · Cochrane Headline outcomes only
RR 0.89 [0.57, 1.38]8 studies · 440 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Benzodiazepines for schizophrenia
2012 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.