Intervention not reported
Milnacipran high dose RCTs: 7 Participants: 2837 · people with chronic pain Interventions: amitriptyline standard dose (25‐75 mg); desvenlafaxine high dose (> 50 mg); duloxetine low dose (<…
1 finding from 1 review
no estimate extracted
7 participants
Very low
Intervention not reported
Esreboxetine standard dose RCTs: 1 Participants: 783 · people with chronic pain Interventions: amitriptyline standard dose (25‐75 mg); desvenlafaxine high dose (> 50 mg); duloxetine low dose (<…
1 finding from 1 review
no estimate extracted
1 participants
Very low
Participant‐reported pain relief of 30% or greater · children and adolescents with chronic non‐cancer pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participant‐reported pain relief of 50% or greater · children and adolescents with chronic non‐cancer pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient Global Impression of Change much or very much improved · children and adolescents with chronic non‐cancer pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Any adverse events · children and adolescents with chronic non‐cancer pain
1 finding from 1 review
Serious adverse events · children and adolescents with chronic non‐cancer pain
1 finding from 1 review
Withdrawals due to adverse events · children and adolescents with chronic non‐cancer pain
1 finding from 1 review
Migraine duration Hours · patients for whom migraine preventive interventions are indicated
1 finding from 1 review
Symptomatic/analgesic medication use for acute headache attacks · patients for whom migraine preventive interventions are indicated
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Migraine index · patients for whom migraine preventive interventions are indicated
1 finding from 1 review
Quality of life · patients for whom migraine preventive interventions are indicated
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participants who withdraw because of an adverse event or any other reason · patients for whom migraine preventive interventions are indicated
SSRIs or SNRIs showed no clear difference in withdrawn (for any reasons and due to adverse events) compared with amitriptyline (low certainty).
1 finding from 1 review
Migraine frequency Number of attacks · patients for whom migraine preventive interventions are indicated
1 finding from 1 review
Migraine intensity Score · patients for whom migraine preventive interventions are indicated
1 finding from 1 review
Intervention not reported
At least 50% reduction in pain or equivalent (substantial) · adults with fibromyalgia
It is very uncertain whether the intervention changes at least 50% reduction in pain or equivalent (substantial) (very low certainty).
1 finding from 1 review
Intervention not reported
At least 30% reduction in pain or equivalent (moderate) · adults with fibromyalgia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Adverse event withdrawals · adults with fibromyalgia
It is very uncertain whether the intervention changes adverse event withdrawals (very low certainty).
1 finding from 1 review
Intervention not reported
Serious adverse events · adults with fibromyalgia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Death · adults with fibromyalgia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found