Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

489 questions · 504 findings · 104 reviews

No studies found 32 · 6.3%GRADE not reported 63 · 12.5%Very low 152 · 30.2%Low 133 · 26.4%Moderate 103 · 20.4%High 21 · 4.2%

Intervention not reported

All‐cause mortality at 2 days ‐ immediate treatment · patients with acute myocardial infarction or stroke1

It is very uncertain whether the intervention changes all‐cause mortality at 2 days ‐ immediate treatment (very low certainty).

1 finding from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Mastectomy skin flap necrosis (number of women with mastectomy skin flap necrosis within 30 days after surgery) · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes mastectomy skin flap necrosis (number of women with mastectomy skin… compared with clinical evaluation (very low certainty).

1 finding from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Infection (number of breasts with infection within 30 days after surgery) · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes infection (number of breasts with infection within 30 days after… compared with clinical evaluation (very low certainty).

1 finding from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Haematoma (number of breasts with haematoma within 30 days after surgery) · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes haematoma (number of breasts with haematoma within 30 days after… compared with clinical evaluation (very low certainty).

1 finding from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Seroma (30 days) · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes seroma (number of breast with seroma within 30 days after surgery) compared with clinical evaluation (very low certainty).

2 findings from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Reoperation · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes reoperation (number of women that were operated again within 30 days… compared with clinical evaluation (very low certainty).

2 findings from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Dehiscence · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes dehiscence (number of women with dehiscence within 30 days after… compared with clinical evaluation (very low certainty).

1 finding from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Infection (number of women with infection of the skin flap or implant within 30 days after surgery) · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes infection (number of women with infection of the skin flap or… compared with clinical evaluation (very low certainty).

1 finding from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Haematoma (proportion of participants in each group with haematoma; · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes haematoma (number of women with haematoma within 30 days after… compared with clinical evaluation (very low certainty).

1 finding from 1 review

Indocyanine Green Angiography (ICGA) vs clinical evaluation

Mastectomy skin flap necrosis (number of breasts with mastectomy skin flap necrosis within 30 days after surgery) · women undergoing immediate breast reconstruction following mastectomy

It is very uncertain whether indocyanine Green Angiography (ICGA) changes mastectomy skin flap necrosis (number of breasts with mastectomy… compared with clinical evaluation (very low certainty).

1 finding from 1 review

Delayed chemotherapy vs immediate chemotherapy

Nausea and vomiting · patients with asymptomatic, incurable, metastatic colorectal cancer

It is very uncertain whether delayed chemotherapy changes toxicity – nausea and vomiting compared with immediate chemotherapy (very low certainty).

1 finding from 1 review