Cochrane · systematic review · CD006406
Bone marrow harvest versus peripheral stem cell collection for haemopoietic stem cell donation in healthy donors
Siddiq, S, Pamphilon, D, Brunskill, S, et al. · Cochrane Database of Systematic Reviews · 2009 · Cochrane Library
HaematologyAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 75%Moderate 1 · 25%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: Haemopoietic stem cell donors
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality (0 to 26 months) | RR 0.25 [0.05, 2.15] | 3 studies · 189 participants | Moderate |
Adverse events (day 7 to day 30 post‐donation) | no estimate extracted | 6 studies · 656 participants | Low |
Pain subsequent to donation ("after collection" ‐ day 30 post‐donation) | no estimate extracted | 6 studies · 656 participants | Low |
Psychological morbidity (immediately ‐ day 28 post‐donation) | no estimate extracted | 3 studies · 214 participants | Low |