Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,432 questions · 1,467 findings · 116 reviews · Headline outcomes only

No studies found 232 · 15.8%GRADE not reported 202 · 13.8%Very low 286 · 19.5%Low 327 · 22.3%Moderate 286 · 19.5%High 134 · 9.1%

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs lidocaine intraperitoneal instillation alone

Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia

Combination of lidocaine intraperitoneal instillation plus… showed no clear difference in number of women requiring rescue medication compared with lidocaine intraperitoneal instillation alone (low certainty).

1 finding from 1 review

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs IM morphine

Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia

Combination of lidocaine intraperitoneal instillation plus… may leads to lower number of women requiring rescue medication compared with intramuscular morphine alone (low certainty).

1 finding from 1 review

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs placebo

Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia

Combination of intraperitoneal lidocaine instillation and… may leads to lower number of women requiring rescue medication compared with placebo (low certainty).

1 finding from 1 review

Thromboelastography (TEG) or thromboelastometry (ROTEM) in combination with SLT or other devices vs clinical judgement or usual care

All‐cause mortality · adults or children with bleeding

Thromboelastography (TEG) or thromboelastometry (ROTEM) in… may leads to lower mortality compared with clinical judgement or usual care (low certainty).

1 finding from 1 review

Thromboelastography (TEG) or thromboelastometry (ROTEM) in combination with SLT or other devices vs clinical judgement or usual care

Proportion of patients receiving PRBCs · adults or children with bleeding

Thromboelastography (TEG) or thromboelastometry (ROTEM) in… may leads to lower proportion of patients receiving PRBCs compared with clinical judgement or usual care (low certainty).

1 finding from 1 review