Adverse effects: pain on injection (solution deposition), Heft-Parker VAS 0-170 mm · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
4% articaine, 1:100,000 epinephrine showed no clear difference in adverse effects: pain on injection (solution deposition),… compared with 2% lidocaine, 1:100,000 epinephrine (moderate certainty).
1 finding from 1 review
Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
The review found no eligible studies for this question.
1 finding from 1 review
SoF: Not measured.
0 studies
No studies found
Adverse effects: pain following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
4% articaine, 1:100,000 epinephrine probably leads to higher adverse effects: pain following injection, Heft-Parker VAS 0-170 mm compared with 2% lidocaine, 1:100,000 epinephrine (moderate certainty).
1 finding from 1 review
Intervention not reported
Mode 1: Anterior sub‐Tenon injections (subconjunctival) · participants undergoing cataract surgery
1 finding from 1 review
no estimate extracted
77015 participants
Moderate
Intervention not reported
Mode 2: Posterior sub‐Tenon injections (retrobulbar) · participants undergoing cataract surgery
1 finding from 1 review
no estimate extracted
77015 participants
Moderate
Repeated need for rapid tranquillisation ‐ needing additional injection during 24 hours · patients with psychosis‐induced aggression or agitation
It is very uncertain whether HALOPERIDOL changes repeated need for rapid tranquillisation ‐ needing additional… compared with COMBINATIONS: b. HALOPERIDOL + LORAZEPAM (very low certainty).
1 finding from 1 review
Repeated need for rapid tranquillisation ‐ more than 1 injection · patients with psychosis‐induced aggression or agitation
It is very uncertain whether HALOPERIDOL changes repeated need for rapid tranquillisation ‐ more that 1 injection compared with OTHER ANTIPSYCHOTIC: b. CHLORPROMAZINE (very low certainty).
1 finding from 1 review
Repeated need for tranquillisation ‐ needing additional injections during 24 hours · patients with psychosis‐induced aggression or agitation
HALOPERIDOL may leads to lower repeated need for tranquillisation needing additional injection… compared with PLACEBO/NIL (low certainty).
1 finding from 1 review
Repeated need for rapid tranquillisation ‐ more than 1 injection · psychosis‐induced aggression or agitation
HALOPERIDOL probably leads to higher repeated need for rapid tranquillisation ‐ more than 1 injection compared with OTHER ANTIPSYCHOTIC: c. DROPERIDOL (moderate certainty).
1 finding from 1 review
Repeated need for rapid tranquillisation ‐ more than 3 injections · patients with psychosis‐induced aggression or agitation
It is very uncertain whether HALOPERIDOL changes repeated need for rapid tranquillisation ‐ more than 3 injections compared with OTHER ANTIPSYCHOTIC: k. ZUCLOPENTHIXOL ACETATE (very low certainty).
1 finding from 1 review
Repeated need for rapid tranquillisation ‐ needing additional injection · patients with psychosis‐induced aggression or agitation
HALOPERIDOL may leads to lower repeated need for rapid tranquillisation ‐ needing additional… compared with OTHER ANTIPSYCHOTIC: a. ARIPIPRAZOLE (low certainty).
1 finding from 1 review
Repeated need for rapid tranquillisation ‐ more than 1 injection · patients with psychosis‐induced aggression or agitation
It is very uncertain whether HALOPERIDOL changes repeated need for rapid tranquillisation more than 1 injection compared with BENZODIAZEPINE: b. LORAZEPAM (very low certainty).
1 finding from 1 review
Intervention not reported
PIPP score during post‐injection period Range of scale 0‐21 for infants < 28 weeks PMA and 0‐18 for infants > 36 weeks PMA A lower score = less pain (Stevens 1996; Stevens 2014a) · neonates with pain associated with venipuncture
1 finding from 1 review
Intervention not reported
DAN score during the post‐injection period Range of scale 0‐10 A lower score = less pain (Carbajal 1997) · neonates with pain associated with venipuncture
1 finding from 1 review
All pain scores during injection Due to range of pain scores used, data analysed using SMDs. Pain scores were measured during and up to 3 minutes following completion of vaccination. · Infants 1 to 12 months during vaccination
2 findings from 1 review
Heart rate · Infants 1 to 12 months during vaccination
1 finding from 1 review
Injection site reactions ‐ induration ‐ swelling · patients with local and systemic reactions
Local and systemic reactions after administration of Tetanus… showed no clear difference in injection site reactions ‐ induration ‐ swelling compared with saline placebo (moderate certainty).
1 finding from 1 review
Injection site pain · patients with local and systemic reactions
Local and systemic reactions after administration of Tetanus… probably leads to higher injection site reactions ‐ pain at injection site compared with saline placebo (moderate certainty).
1 finding from 1 review
Injection site reactions ‐ erythema ‐ redness · patients with local and systemic reactions
Local and systemic reactions after administration of Tetanus… showed no clear difference in injection site reactions ‐ erythema ‐ redness compared with saline placebo (moderate certainty).
1 finding from 1 review
Need for additional injection Number of additional injections · patients undergoing cataract surgery
Peribulbar showed no clear difference in need for additional injection Number of additional injections compared with retrobulbar (low certainty).
1 finding from 1 review