Cochrane · systematic review · CD011248

Breastfeeding for procedural pain in infants beyond the neonatal period

Harrison, D, Reszel, J, Bueno, M, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 20%Low 2 · 40%Moderate 2 · 40%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Breastfeeding compared with other interventions, oral water, or no treatment for pain during vaccination in infants 1 to 12 months

Population: Infants 1 to 12 months during vaccination
5 questions
OutcomeEffectEvidenceStatus / GRADE
Cry duration Seconds cry time during procedure or proportion of crying during procedure. Crying was measured during and up to 3 minutes following completion of vaccination.
Breastfeeding vs other interventions, oral water, or no treatment
no estimate extracted6 studies · 547 participantsModerate
All pain scores during injection Due to range of pain scores used, data analysed using SMDs. Pain scores were measured during and up to 3 minutes following completion of vaccination.
Breastfeeding vs other interventions, oral water, or no treatment
no estimate extracted5 studies · 310 participantsModerate
NIPS score during injection The NIPS was measured during and up to 3 minutes following completion of vaccination.
Breastfeeding vs other interventions, oral water, or no treatment
no estimate extracted3 studies · 174 participantsLow
Heart rate after injection Heart rate in the period following completion of the injections was measured in 2 studies.
Breastfeeding vs other interventions, oral water, or no treatment
no estimate extracted2 studies · 186 participantsLow
Adverse events
Breastfeeding vs other interventions, oral water, or no treatment
no estimate extractedNRVery low