What do systematic reviews say?

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

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No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Intervention not reported

Mean time from injection to placenta removal Mean time from injection to placenta removal. · women with retained placenta

1 finding from 1 review

Prostaglandins for management of retained placenta 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 99 participants
Very low

Intervention not reported

Maternal pain between injection and discharge from labour ward Maternal pain between injection and discharge from labour ward · women with retained placenta

It is very uncertain whether the intervention changes maternal pain between injection and discharge from labour ward… (very low certainty).

1 finding from 1 review

Prostaglandins for management of retained placenta 2014 · Cochrane Headline outcomes only
RR 0.91 [0.43, 1.96]
2 studies · 124 participants
Very low

Intervention not reported

Nausea between injection and discharge from labour ward Nausea between injection and discharge from labour ward · women with retained placenta

It is very uncertain whether the intervention changes nausea between injection and discharge from labour ward Nausea… (very low certainty).

1 finding from 1 review

Prostaglandins for management of retained placenta 2014 · Cochrane Headline outcomes only
RR 1.72 [0.15, 19.41]
2 studies · 124 participants
Very low

Antibiotics vs antibiotics alone

Maternal death · women in labor with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
GRADE not reported

Antibiotics vs no treatment during postpartum period

Postpartum endometritis · women with management of intra‐amniotic infection

It is very uncertain whether antibiotics changes postpartum endometritis compared with no treatment during postpartum period (very low certainty).

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
RR 1.48 [0.68, 3.24]
1 study · 116 participants
Very low

Antibiotics vs no treatment during postpartum period

Duration of maternal and neonatal hospital stay · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Antibiotics vs no treatment during postpartum period

Need for additional antibiotic therapy · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Antibiotics vs no treatment during postpartum period

Postpartum readmission for endometritis · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Antibiotics vs no treatment during postpartum period

Failure of treatment · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Antibiotics vs placebo during postpartum period

Maternal and neonatal mortality · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Antibiotics vs placebo during postpartum period

Maternal and neonatal severe infection · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Antibiotics vs placebo during postpartum period

Duration of maternal and neonatal hospital stay · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Antibiotics vs placebo during postpartum period

Endomyometritis · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 288 participants
GRADE not reported

Antibiotics vs placebo during postpartum period

Need for additional antibiotic therapy · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Antibiotics vs antibiotics alone

Neonatal death (baby born alive at any gestation and dies within 28 days) · women in labor with management of intra‐amniotic infection

It is very uncertain whether antibiotics changes neonatal deaths compared with antibiotics (very low certainty).

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
RR 1.39 [0.24, 8.06]
1 study · 133 participants
Very low

Antibiotics vs placebo during postpartum period

Postpartum readmission for endometritis · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Antibiotics vs placebo during postpartum period

Treatment failure · women with management of intra‐amniotic infection

It is very uncertain whether antibiotics changes treatment failure compared with placebo during postpartum period (very low certainty).

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
RR 0.97 [0.14, 6.77]
2 studies · 288 participants
Very low

Antibiotics vs antibiotics during postpartum period

Maternal and neonatal mortality · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Antibiotics vs antibiotics during postpartum period

Maternal and neonatal severe infection · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Antibiotics vs antibiotics during postpartum period

Length of treatment · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 131 participants
Very low