Cochrane · systematic review · CD010312

Prostaglandins for management of retained placenta

Grillo‐Ardila, CF, Ruiz‐Parra, AI, Gaitán, HG, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 7 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

prostaglandins for retained placenta

Population: women with retained placenta
7 questions
OutcomeEffectEvidenceStatus / GRADE
Manual removal of placenta Manual removal after intervention
RR 0.82 [0.54, 1.27]3 studies · 244 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Severe postpartum haemorrhage Objectively or subjectively measured after intervention/Estimated blood loss in ML.
RR 0.8 [0.55, 1.15]2 studies · 194 participantsVery low
Downgraded: risk of bias, imprecision
Blood transfusion Blood transfusion during puerperium
RR 0.72 [0.43, 1.22]3 studies · 244 participantsVery low
Downgraded: risk of bias, imprecision
Mean blood loss Objectively or subjectively measured after intervention/Mean blood loss in ML.
no estimate extracted3 studies · 244 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Mean time from injection to placenta removal Mean time from injection to placenta removal.
no estimate extracted1 study · 99 participantsVery low
Downgraded: risk of bias, imprecision
Maternal pain between injection and discharge from labour ward Maternal pain between injection and discharge from labour ward
RR 0.91 [0.43, 1.96]2 studies · 124 participantsVery low
Downgraded: risk of bias, imprecision
Nausea between injection and discharge from labour ward Nausea between injection and discharge from labour ward
RR 1.72 [0.15, 19.41]2 studies · 124 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency