Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,231 questions · 3,354 findings · 394 reviews

No studies found 803 · 23.9%GRADE not reported 267 · 8%Very low 757 · 22.6%Low 859 · 25.6%Moderate 486 · 14.5%High 182 · 5.4%

Total or near‐total thyroidectomy vs subtotal thyroidectomy

a)Goitre recurrence b)Re‐intervention due to goitre recurrence

Total or near‐total thyroidectomy probably leads to lower a)Goitre recurrence b)Re‐intervention due to goitre recurrence compared with subtotal thyroidectomy (moderate certainty).

1 finding from 1 review

Total or near‐total thyroidectomy vs subtotal thyroidectomy

Adverse events: a) Permanent recurrent laryngeal nerve palsy b) Permanent hypoparathyroidism

Total or near‐total thyroidectomy showed no clear difference in adverse events: a) Permanent recurrent laryngeal nerve palsy b)… compared with subtotal thyroidectomy (low certainty).

1 finding from 1 review

Monotherapy vs combination therapy compared

Clinical failure—same beta lactam Antibiotic modifications · patients with sepsis

It is very uncertain whether monotherapy changes clinical failure—same beta lactam Antibiotic modifications compared with combination therapy compared (very low certainty).

1 finding from 1 review

Monotherapy vs combination therapy compared

Clinical failure—different beta lactam Antibiotic modifications · patients with sepsis

It is very uncertain whether monotherapy changes clinical failure—different beta lactam Antibiotic modifications compared with combination therapy compared (very low certainty).

1 finding from 1 review

Intervention not reported

"Moderate" benefit At least 30% reduction in pain · Adults with cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Patient Global Impression of Change much or very much improved · Adults with cancer pain

The review found no eligible studies for this question.

1 finding from 1 review