Unacceptable restoration (poor marginal integrity / restoration removal) · Partially edentulous patients receiving tooth-supported FDPs
Titanium framework FDP led to higher unacceptable restoration (poor marginal integrity / restoration… compared with high-gold content alloy framework FDP; GRADE not reported.
1 finding from 1 review
Bleeding: Numbers of patients with at least one significant bleeding event · People with a haematological disorder
Prophylactic platelet transfusion at threshold of 10,000 showed no clear difference in bleeding: Numbers of patients with at least one significant bleeding… compared with higher transfusion threshold (20,000 or 30,000) (moderate certainty).
1 finding from 1 review
Mortality: secondary to bleeding · People with a haematological disorder
Prophylactic platelet transfusion at threshold of 10,000 showed no clear difference in mortality: secondary to bleeding compared with higher transfusion threshold (20,000 or 30,000) (low certainty).
1 finding from 1 review
5-year prosthesis survival · Partially edentulous patients receiving tooth-supported FDPs
1 finding from 1 review
Laboratory cost per unit · Patients receiving crowns and FDPs; split-mouth, 10-year
1 finding from 1 review
Locoregional control · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Low dose rate interstitial radiotherapy showed no clear difference in locoregional control compared with high dose rate interstitial radiotherapy; GRADE not reported.
1 finding from 1 review
Presence/absence of HSV oral lesions · Patients being treated for cancer (acute leukaemia; chemotherapy or stem-cell transplantation)
Prophylactic valaciclovir (lower dose) showed no clear difference in presence/absence of HSV oral lesions compared with prophylactic valaciclovir (higher dose); GRADE not reported.
1 finding from 1 review
Viral isolates · Patients being treated for cancer (acute leukaemia; chemotherapy or stem-cell transplantation)
1 finding from 1 review
Orlowski 2004: 182 throat swabs performed for patients receiving 500 mg of valaciclovir (n = 40) and 198 swabs for those receiving 1000 mg (n = 41); all of the cultures proved negative (1 trial, 81; not estimable).
1 study · 81 participants
GRADE not reported
Adverse effects · Patients being treated for cancer (acute leukaemia; chemotherapy or stem-cell transplantation)
1 finding from 1 review
One study reported adverse effects (Warkentin 2002). Twenty patients allocated to receive high dose valaciclovir reported adverse effects (42%); for the low dose group this number was 27 (52%). Adverse effects were…
1 study · 100 participants
GRADE not reported
Death · patients treated for acute bacterial meningitis
1 finding from 1 review
Death: Low/middle‐income countries · patients treated for acute bacterial meningitis
1 finding from 1 review
Deafness · patients treated for acute bacterial meningitis
1 finding from 1 review
Deafness: low‐income countries · patients treated for acute bacterial meningitis
1 finding from 1 review
Mortality before hospital discharge · preterm infants with respiratory distress for initial respiratory support
It is very uncertain whether nHFV changes mortality before hospital discharge compared with invasive respiratory therapy (very low certainty).
1 finding from 1 review
Death or chronic lung disease · newborn (term* and preterm) infants with respiratory distress for initial respiratory support
nHFV showed no clear difference in death or chronic lung disease compared with nCPAP used (low certainty).
1 finding from 1 review
Intraventricular haemorrhage, Papile grade 3/4 · newborn (term* and preterm) infants with respiratory distress for initial respiratory support
nHFV showed no clear difference in intraventricular haemorrhage, Papile grade 3/4 compared with nCPAP used (low certainty).
1 finding from 1 review
Neurodevelopmental disability · newborn (term* and preterm) infants with respiratory distress for initial respiratory support
1 finding from 1 review
Mortality before hospital discharge · preterm infants with respiratory distress for initial respiratory support
nHFV showed no clear difference in mortality before hospital discharge compared with nIPPV used (low certainty).
1 finding from 1 review
Endotracheal intubation To discharge · preterm infants with respiratory distress for initial respiratory support
nHFV showed no clear difference in endotracheal intubation To discharge compared with nIPPV used (low certainty).
1 finding from 1 review
Chronic lung disease · preterm infants with respiratory distress for initial respiratory support
nHFV may leads to lower chronic lung disease compared with nIPPV used (low certainty).
1 finding from 1 review