Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Intervention not reported

Caesarean section · women in late pregnancy (after 24 weeks' gestation) in both unselected populations and designated low‐risk populations

The intervention showed no clear difference in caesarean section (high certainty).

1 finding from 1 review

Intervention not reported

Preterm delivery less than 34 weeks · women in late pregnancy (after 24 weeks' gestation) in both unselected populations and designated low‐risk populations
1 finding from 1 review

Intervention not reported

Maternal psychological effects · women in late pregnancy (after 24 weeks' gestation) in both unselected populations and designated low‐risk populations
1 finding from 1 review

Intervention not reported

Neurodevelopment at age 2 · women in late pregnancy (after 24 weeks' gestation) in both unselected populations and designated low‐risk populations
1 finding from 1 review

Prophylactic antibiotics vs placebo

Preterm prelabour rupture of membranes · women in the second or third trimester of pregnancy before labour and delivery

Prophylactic antibiotics showed no clear difference in preterm prelabour rupture of membranes compared with placebo (low certainty).

1 finding from 1 review

Prophylactic antibiotics vs placebo

Puerperal sepsis/postpartum endometritis · women in the second or third trimester of pregnancy before labour and delivery

Prophylactic antibiotics probably leads to lower puerperal sepsis/postpartum endometritis compared with placebo (moderate certainty).

1 finding from 1 review

Case notes vs control

Women who felt in control · pregnant women from the time of their first antenatal visit to the end of the puerperium

Case notes probably leads to higher women who felt in control compared with control (moderate certainty).

1 finding from 1 review

Case notes vs control

Satisfaction with antenatal care (possible values 81‐405, Littlefield 1987) · pregnant women from the time of their first antenatal visit to the end of the puerperium

Case notes showed no clear difference in women's satisfaction with antenatal care compared with control (low certainty).

1 finding from 1 review

Case notes vs control

Women who wanted to carry case notes in subsequent pregnancy · pregnant women from the time of their first antenatal visit to the end of the puerperium

Case notes may leads to higher women who wanted to carry case notes in subsequent pregnancy compared with control (low certainty).

1 finding from 1 review

Case notes vs control

Breastfeeding · pregnant women from the time of their first antenatal visit to the end of the puerperium

Case notes showed no clear difference in breastfeeding compared with control (moderate certainty).

1 finding from 1 review

Case notes vs control

Epidural analgesia during labour · pregnant women from the time of their first antenatal visit to the end of the puerperium

Case notes showed no clear difference in epidural analgesia used in labour compared with control (low certainty).

1 finding from 1 review

Case notes vs control

Caesarean section · pregnant women from the time of their first antenatal visit to the end of the puerperium

Case notes probably leads to higher caesarean section compared with control (moderate certainty).

1 finding from 1 review

Case notes vs control

Fetal or neonatal mortality · pregnant women from the time of their first antenatal visit to the end of the puerperium

Case notes showed no clear difference in stillbirth or neonatal death compared with control (moderate certainty).

1 finding from 1 review

Local and systemic reactions after administration of Tetanus Diphtheria acelluar Pertussis vaccine vs saline placebo

Injection site reactions ‐ induration ‐ swelling · patients with local and systemic reactions

Local and systemic reactions after administration of Tetanus… showed no clear difference in injection site reactions ‐ induration ‐ swelling compared with saline placebo (moderate certainty).

1 finding from 1 review

Local and systemic reactions after administration of Tetanus Diphtheria acelluar Pertussis vaccine vs saline placebo

Systemic reactions ‐ fever (oral temperature ≥ 38°C) · patients with local and systemic reactions

Local and systemic reactions after administration of Tetanus… showed no clear difference in systemic reactions ‐ fever (oral temperature ≥ 38°C) compared with saline placebo (moderate certainty).

1 finding from 1 review