Dental fluorosis of aesthetic concern (Dean's Index, TFI, TSIF) · Populations of all ages (mostly children) exposed to drinking water with differing fluoride concentrations
Higher water fluoride concentration (fluoridated water; natural or… may leads to higher dental fluorosis of aesthetic concern (Dean's Index, TFI, TSIF) compared with lower water fluoride concentration (concurrent control) (low certainty).
1 finding from 1 review
Adverse effects: dental fluorosis · Populations of all ages (mostly children) exposed to drinking water with differing fluoride concentrations
Higher water fluoride concentration (fluoridated water; natural or… may leads to higher dental fluorosis of any level (all severities) compared with lower water fluoride concentration (concurrent control) (low certainty).
1 finding from 1 review
Dental caries · Adults (≥18 years)
After adjustment for confounders, obesity/overweight was not associated with dental caries (OR 1.00, 95% CI 0.89 to 1.12; ungraded).
9 findings from 1 review
Multimorbidity patterns of dental caries and obesity/overweight among adults: a systematic review and meta-analysis. 2025 All outcomesPopulation-based cross-sectional studies; adults ≥18 years; 6 countries (Turkey, Portugal, China, Japan, Saudi Arabia, Israel, South Korea) · By confounder adjustment: adjusted
OR 1.00 [0.89, 1.12]
Studies not reported
GRADE not reported
Multimorbidity patterns of dental caries and obesity/overweight among adults: a systematic review and meta-analysis. 2025 All outcomesPopulation-based cross-sectional studies; adults ≥18 years; 6 countries (Turkey, Portugal, China, Japan, Saudi Arabia, Israel, South Korea) · By region: West Asia
OR 1.23 [0.96, 1.50]
Studies not reported
GRADE not reported
Multimorbidity patterns of dental caries and obesity/overweight among adults: a systematic review and meta-analysis. 2025 All outcomesPopulation-based cross-sectional studies; adults ≥18 years; 6 countries (Turkey, Portugal, China, Japan, Saudi Arabia, Israel, South Korea) · By BMI classification: overweight (vs study-defined non-overweight: normal or low weight)
OR 0.99 [0.98, 1.00]
Studies not reported
GRADE not reported
Show 6 more findings
Oral mucositis (severe) · breast cancer patients undergoing chemotherapy
Granulocyte-macrophage colony-stimulating factor (GM-CSF), higher… led to higher oral mucositis (severe) compared with granulocyte-macrophage colony-stimulating factor (GM-CSF), lower…; GRADE not reported.
1 finding from 1 review
Prevalence and severity of oral and TMJ diseases/conditions (periodontal status and dental caries) · Children and adolescents with juvenile idiopathic arthritis (JIA)
Some studies suggested greater JIA disease activity/severity (and certain medications) was associated with worse periodontal and caries outcomes, but small samples meant no solid conclusion could be drawn (ungraded).
1 finding from 1 review
Odds of higher caries (DMFT) category · 12-year-old children across European countries (national/regional epidemiological surveys, 2011-2022)
In the adjusted ordinal model geographical location was not independently significant for DMFT category (OR 0.57, 95% CI 0.24 to 1.35); not GRADE-rated.
1 finding from 1 review
Odds of higher caries (DMFT) category · 12-year-old children across European countries (national/regional epidemiological surveys, 2011-2022)
HDI was not independently associated with DMFT category in the adjusted model (OR 1.82, 95% CI 0.32 to 10.47); not GRADE-rated.
1 finding from 1 review
Pain VAS 0‐100 (higher means worse) · carpal tunnel syndrome
1 finding from 1 review
CTS symptoms (Boston CTS questionnaire) ‐ long‐term improvement: > 3 monthsScale: 1 to 5, higher is worse · carpal tunnel syndrome
1 finding from 1 review
Function (Boston CTS questionnaire) ‐ Long‐term improvement: > 3 monthsScale: 1 to 5, higher is worse · carpal tunnel syndrome
1 finding from 1 review
Health‐related quality of life (EQ‐5D) ‐ Long‐term improvement: > 3 months Scale: 0 to 1, higher is better · carpal tunnel syndrome
1 finding from 1 review
Treatment non‐acceptability (higher = greater non‐acceptability): end‐of‐intervention · older people with depression
1 finding from 1 review
Quality of life or psychological well‐being (higher = higher quality of life or psychological well‐being): end‐of‐intervention · older people with depression
1 finding from 1 review
Parent health, functioning, and quality of life Patient‐Reported Outcomes Measurement Information System (PROMIS) (higher scores = more of the outcome of interest, which can mean improvement or deterioration depending on the outcome) · children with medical complexity
1 finding from 1 review
Child and family satisfaction with, and perceptions of, care and service delivery Family Experiences With Coordination of Care (FECC) survey (higher scores = better) Consumer Assessment of Healthcare Providers and Systems (CAHPS) (higher scores = ... · children with medical complexity
1 finding from 1 review
Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
2 findings from 1 review
Pain (POSAS 0–10, higher score = more severe pain, VAS 0–10, higher score = more severe pruritus) · people with burn wounds likely to develop hypertrophic scarring
1 finding from 1 review
Pruritus · people with burn wounds likely to develop hypertrophic scarring
1 finding from 1 review
QoL · people with burn wounds likely to develop hypertrophic scarring
1 finding from 1 review
Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
2 findings from 1 review