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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.
75,239 questions in 5,342 reviews
current versionsNo studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intervention NR Severe neutropenia (WHO grade IV) Rates of patients · breast cancer patients undergoing chemotherapy Primary prophylactic colony‐stimulating factors for the prevention of chemotherapy‐induced febrile… (2012) · Cochrane | RR 0.44 [0.17, 1.18] | 4 studies · 712 participants | Moderate |
Intervention NR Infections Rates of patients · breast cancer patients undergoing chemotherapy Primary prophylactic colony‐stimulating factors for the prevention of chemotherapy‐induced febrile… (2012) · Cochrane | RR 0.86 [0.72, 1.02] | 3 studies · 210 participants | Low |
Intervention NR Hospitalization Rates of patients · breast cancer patients undergoing chemotherapy Primary prophylactic colony‐stimulating factors for the prevention of chemotherapy‐induced febrile… (2012) · Cochrane | RR 0.14 [0.06, 0.3] | 4 studies · 1149 participants | Low |
Intervention NR Antibiotics (i.v.) Rates of patients · breast cancer patients undergoing chemotherapy Primary prophylactic colony‐stimulating factors for the prevention of chemotherapy‐induced febrile… (2012) · Cochrane | RR 0.35 [0.22, 0.55] | 4 studies · 1568 participants | Low |
Intervention NR Chemotherapy Rates of patients who received the planned chemotherapy doses at scheduled times and doses · breast cancer patients undergoing chemotherapy Primary prophylactic colony‐stimulating factors for the prevention of chemotherapy‐induced febrile… (2012) · Cochrane | RR 1.05 [0.97, 1.13] | 4 studies · 1588 participants | Low |
Intervention NR Bone pain Rates of patients · breast cancer patients undergoing chemotherapy Primary prophylactic colony‐stimulating factors for the prevention of chemotherapy‐induced febrile… (2012) · Cochrane | RR 5.88 [2.54, 13.6] | 3 studies · 388 participants | Moderate |
Azithromycin (single‐ or two‐dose) vs penicillin HIV seroconversion ‐ penicillin vs single‐dose azithromycin · patients with syphilis Genital ulcer disease treatment for reducing sexual acquisition of HIV (2012) · Cochrane | no estimate extracted | 1 study · 19 participants | Very low |
Azithromycin (single‐ or two‐dose) vs penicillin HIV seroconversion ‐ penicillin vs two‐dose azithromycin · patients with syphilis Genital ulcer disease treatment for reducing sexual acquisition of HIV (2012) · Cochrane | no estimate extracted | 1 study · 22 participants | Very low |
Fleroxacin 200 mg or TMP‐SMZ vs fleroxacin 400 mg HIV seroconversion ‐ fleroxacin 400 mg vs fleroxacin 200 mg · patients with chancroid Genital ulcer disease treatment for reducing sexual acquisition of HIV (2012) · Cochrane | RR 3 [0.29, 30.69] | 1 study · 45 participants | Very low |
Fleroxacin 200 mg or TMP‐SMZ vs fleroxacin 400 mg HIV seroconversion ‐ fleroxacin 400 mg vs TMP‐SMZ · patients with chancroid Genital ulcer disease treatment for reducing sexual acquisition of HIV (2012) · Cochrane | RR 0.33 [0.04, 3.09] | 1 study · 98 participants | Very low |
Intervention NR Exchange transfusion · preterm or low birth weight infants Prophylactic phototherapy for preventing jaundice in preterm or low birth weight infants (2012) · Cochrane | RR 0.22 [0.15, 0.34] | 3 studies · 2946 participants | Moderate |
Intervention NR Cerebral palsy · preterm or low birth weight infants Prophylactic phototherapy for preventing jaundice in preterm or low birth weight infants (2012) · Cochrane | RR 0.96 [0.5, 1.85] | 2 studies · 756 participants | Moderate |
Intervention NR Peak serum bilirubin · preterm or low birth weight infants Prophylactic phototherapy for preventing jaundice in preterm or low birth weight infants (2012) · Cochrane | no estimate extracted | 6 studies · 2319 participants | Low |
Intervention NR Serum bilirubin greater than 10 mg/dl · preterm or low birth weight infants Prophylactic phototherapy for preventing jaundice in preterm or low birth weight infants (2012) · Cochrane | RR 0.27 [0.22, 0.33] | 3 studies · 1090 participants | Moderate |
Intervention NR Retinopathy of prematurity · preterm or low birth weight infants Prophylactic phototherapy for preventing jaundice in preterm or low birth weight infants (2012) · Cochrane | RR 0.93 [0.77, 1.13] | 2 studies · 1687 participants | High |
Intervention NR All‐cause mortality · preterm or low birth weight infants Prophylactic phototherapy for preventing jaundice in preterm or low birth weight infants (2012) · Cochrane | RR 1.08 [0.93, 1.26] | 4 studies · 3044 participants | Moderate |
Intervention NR Global effect: 1a. Medium‐term ‐ Average end point score on various outcomes ‐ CGI‐severity (low = favourable) ( · schizophrenia Acetylcholinesterase inhibitors for schizophrenia (2012) · Cochrane | no estimate extracted | 1 study · 11 participants | Ungraded |
Intervention NR Leaving the study early ‐ Adverse event: Short‐term · schizophrenia Acetylcholinesterase inhibitors for schizophrenia (2012) · Cochrane | RR 1.91 [0.8, 4.61] | 6 studies · 428 participants | Ungraded |
Intervention NR Mental state: 1b. Average end point score on various outcomes‐PANSS (medium‐term) ‐ Medium‐term ‐ PANSS negative end point score (low = favourable) · schizophrenia Acetylcholinesterase inhibitors for schizophrenia (2012) · Cochrane | no estimate extracted | 2 studies · 31 participants | Ungraded |
Intervention NR Mental state: 1b.Average end point score on various outcomes‐PANSS (medium‐term) ‐ Medium term ‐ PANSS general psychopathology end point score (low = favourable) · schizophrenia Acetylcholinesterase inhibitors for schizophrenia (2012) · Cochrane | no estimate extracted | 2 studies · 31 participants | Ungraded |
Intervention NR Cognitive function: 3. Short‐term ‐ Average end point score on various subscales of WAIS III (high = favourable) ‐ Digit symbol score · schizophrenia Acetylcholinesterase inhibitors for schizophrenia (2012) · Cochrane | no estimate extracted | 1 study · 73 participants | Ungraded |
Intervention NR Cognitive function: 4. Short‐term ‐ Average end point score on various subscales of HVLT (high = favourable) ‐ Recognition · schizophrenia Acetylcholinesterase inhibitors for schizophrenia (2012) · Cochrane | no estimate extracted | 2 studies · 48 participants | Ungraded |
Intervention NR Adverse event: 11a. Short‐term ‐ Average end point score on EPSEs scale (low = favourable) ‐ AIMS · schizophrenia Acetylcholinesterase inhibitors for schizophrenia (2012) · Cochrane | no estimate extracted | 1 study · 35 participants | Ungraded |
Summary of findings: Email as additional communication method vs standard methods: Patient participants Patient's understanding · Healthcare usersa Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 1 study · 74 participants | Very low |
Summary of findings: Email as additional communication method vs standard methods: Healthcare professional participants Health professional outcome · Physicians Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings: Email as additional communication method vs standard methods: Healthcare professional participants Harms · Physicians Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings: Email counselling vs telephone counselling Patient health status and wellbeing · Adults (25‐60 years) Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 1 study · 105 participants | Very low |
Summary of findings: Email counselling vs telephone counselling Patient behaviours and actions · Adults (25‐60 years) Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 1 study · 105 participants | Very low |
Summary of findings: Email counselling vs telephone counselling Health service outcomes · Adults (25‐60 years) Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings: Email counselling vs telephone counselling Health professional outcomes · Adults (25‐60 years) Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings: Email counselling vs telephone counselling Harms · Adults (25‐60 years) Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 1 study · 105 participants | Very low |
Summary of findings: Email as additional communication method vs standard methods: Patient participants Patient health status and wellbeing · Healthcare usersa Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 2 studies · 147 participants | Very low |
Summary of findings: Email as additional communication method vs standard methods: Patient participants Patient/caregiver views · Healthcare usersa Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 2 studies · 90 participants | Very low |
Summary of findings: Email as additional communication method vs standard methods: Patient participants Patient behaviours and actions · Healthcare usersa Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 2 studies · 147 participants | Very low |
Summary of findings: Email as additional communication method vs standard methods: Patient participants Health service outcome; resource use · Healthcare usersa Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 3 studies · 379 participants | Very low |
Summary of findings: Email as additional communication method vs standard methods: Patient participants Health professional outcomes · Healthcare usersa Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings: Email as additional communication method vs standard methods: Patient participants Harms · Healthcare usersa Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings: Email as additional communication method vs standard methods: Healthcare professional participants Patient related outcomes · Physicians Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings: Email as additional communication method vs standard methods: Healthcare professional participants Health service outcome; resource use · Physicians Email for clinical communication between patients/caregivers and healthcare professionals (2012) · Cochrane | no estimate extracted | 2 studies · 230 participants | Very low |
Summary of findings: Email communication vs standard mail Patient or caregiver behaviours/actions · Adultsa Email for the provision of information on disease prevention and health promotion (2012) · Cochrane | no estimate extracted | 2 studies · 96 participants | Very low |
Summary of findings: Email communication vs usual care Healthcare professional outcomes · Adultsa Email for the provision of information on disease prevention and health promotion (2012) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings: Email communication vs usual care Harms · Adultsa Email for the provision of information on disease prevention and health promotion (2012) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings: Email communication vs standard mail Patient or caregiver understanding and support · Adultsa Email for the provision of information on disease prevention and health promotion (2012) · Cochrane | no estimate extracted | 1 study · 44 participants | Very low |
Summary of findings: Email communication vs standard mail Health service outcome: uptake of preventive screening · Adultsa Email for the provision of information on disease prevention and health promotion (2012) · Cochrane | no estimate extracted | 3 studies · 1859 participants | Very low |
Summary of findings: Email communication vs standard mail Healthcare professional outcomes · Adultsa Email for the provision of information on disease prevention and health promotion (2012) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings: Email communication vs standard mail Harms · Adultsa Email for the provision of information on disease prevention and health promotion (2012) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Summary of findings: Email communication vs usual care Patient or caregiver behaviours/actions · Adultsa Email for the provision of information on disease prevention and health promotion (2012) · Cochrane | no estimate extracted | 2 studies · 132 participants | Very low |
Summary of findings: Email communication vs usual care Patient health status and well‐being · Adultsa Email for the provision of information on disease prevention and health promotion (2012) · Cochrane | no estimate extracted | 1 study · 49 participants | Very low |
Summary of findings: Email communication vs usual care Patient or caregiver understanding and support · Adultsa Email for the provision of information on disease prevention and health promotion (2012) · Cochrane | no estimate extracted | 1 study · 49 participants | Very low |
Summary of findings: Email communication vs usual care Health service outcomes · Adultsa Email for the provision of information on disease prevention and health promotion (2012) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |