Cochrane · systematic review · CD007967
Acetylcholinesterase inhibitors for schizophrenia
Singh, J, Kour, K, Jayaram, MB · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library
SchizophreniaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
0
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 7 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: schizophrenia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Global effect: 1a. Medium‐term ‐ Average end point score on various outcomes ‐ CGI‐severity (low = favourable) ( | no estimate extracted | 1 study · 11 participants | Ungraded |
Leaving the study early ‐ Adverse event: Short‐term | RR 1.91 [0.8, 4.61] | 6 studies · 428 participants | Ungraded |
Mental state: 1b. Average end point score on various outcomes‐PANSS (medium‐term) ‐ Medium‐term ‐ PANSS negative end point score (low = favourable) | no estimate extracted | 2 studies · 31 participants | Ungraded |
Mental state: 1b.Average end point score on various outcomes‐PANSS (medium‐term) ‐ Medium term ‐ PANSS general psychopathology end point score (low = favourable) | no estimate extracted | 2 studies · 31 participants | Ungraded |
Cognitive function: 3. Short‐term ‐ Average end point score on various subscales of WAIS III (high = favourable) ‐ Digit symbol score | no estimate extracted | 1 study · 73 participants | Ungraded |
Cognitive function: 4. Short‐term ‐ Average end point score on various subscales of HVLT (high = favourable) ‐ Recognition | no estimate extracted | 2 studies · 48 participants | Ungraded |
Adverse event: 11a. Short‐term ‐ Average end point score on EPSEs scale (low = favourable) ‐ AIMS | no estimate extracted | 1 study · 35 participants | Ungraded |