Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,245 questions · 1,274 findings · 321 reviews

No studies found 247 · 19.4%GRADE not reported 195 · 15.3%Very low 372 · 29.2%Low 282 · 22.1%Moderate 141 · 11.1%High 37 · 2.9%

Summary of findings for exercise plus education vs control

Number of people sustaining one or more fall‐related fractures · people with Parkinson's disease

It is very uncertain whether summary of findings for exercise plus education changes number of people sustaining one or more fall‐related fractures compared with control (very low certainty).

1 finding from 1 review

Exercise vs control

Number of people sustaining one or more fall‐related fractures · people with Parkinson's disease

It is very uncertain whether summary of findings for exercise changes number of people sustaining one or more fall‐related fractures compared with control (very low certainty).

1 finding from 1 review

Weekend therapy vs no topical corticosteroids

Clinician‐reported signs of eczema: number of participants with one or more relapses (16‐20 weeks) · children and adults with mild to severe eczema

Weekend therapy probably leads to lower clinician‐reported signs of eczema: number of participants with one… compared with no topical corticosteroid (moderate certainty).

1 finding from 1 review

Cemented vs uncemented hemiarthroplasty

Mobility, early (within 4 months): able to walk outdoors using no more than 1 walking aid. · adults with displaced and undisplaced hip fractures

Cemented showed no clear difference in mobility, early (within 4 months): able to walk outdoors using no… compared with uncemented hemiarthroplasty (moderate certainty).

1 finding from 1 review

Vitrectomy vs vitreous tap biopsy and antibiotic injection

Improvement in visual acuity at 3 months' · people with endophthalmitis following intraocular surgery

It is very uncertain whether vitrectomy changes proportion of people with a visual acuity improvement of 10 letters… compared with vitreous tap biopsy and antibiotic injection (very low certainty).

1 finding from 1 review

Phacoemulsification vs laser peripheral iridotomy

Progression of visual field loss (worsening of one or more stages, accordingto the Glaucoma Staging System‐2) (at 12 months) · participants with primary angle‐closure glaucoma

Phacoemulsification probably leads to lower progression of visual field loss (worsening of one or more stages,… compared with laser peripheral iridotomy (moderate certainty).

1 finding from 1 review

Antibiotics vs placebo compared

Treatment failure (development of more severe signs and symptoms by the end of treatment) · children, aged 2 to 59 months, with WHO‐defined non‐severe pneumonia and wheeze

Antibiotic therapy may leads to lower treatment failure (development of more severe signs and symptoms by… compared with placebo compared to placebo (low certainty).

1 finding from 1 review