Cochrane · systematic review · CD013030

Digital interventions to improve adherence to maintenance medication in asthma

Chan, A, De Simoni, A, Wileman, V, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library

AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 50%Moderate 3 · 50%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Digital adherence interventions compared to usual care for asthma

Population: asthma
6 questions
OutcomeEffectEvidenceStatus / GRADE
Adherence (percentage of people adhering to their prescribed medication)
Digital adherence interventions vs usual care
no estimate extracted16 studies · 8885 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Asthma control ‐ change from baseline (various scales; higher scores = better asthma control ‐ standardised for different scales, scale reversed if in opposite direction)
Digital adherence interventions vs usual care
no estimate extracted15 studies · 1638 participantsModerate
Asthma exacerbations ‐ Number of people with one or more exacerbations
Digital adherence interventions vs usual care
RR 0.53 [0.32, 0.91]6 studies · 678 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Unscheduled healthcare utilisation ‐ number of hospital or GP/ED visits
Digital adherence interventions vs usual care
RR 0.74 [0.51, 1.06]4 studies · 446 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Lung function ‐ FEV1 % predicted (change from baseline)
Digital adherence interventions vs usual care
no estimate extracted7 studies · 1052 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Quality of life ‐ change from baseline (various scales; higher scores indicate better quality of life)
Digital adherence interventions vs usual care
no estimate extracted10 studies · 848 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency