Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

423 questions · 477 findings · 107 reviews

No studies found 44 · 9.2%GRADE not reported 97 · 20.3%Very low 165 · 34.6%Low 113 · 23.7%Moderate 41 · 8.6%High 17 · 3.6%

Intervention not reported

PTB (< 37w) ‐ PTB (<37w) ‐ Depth ≥15 to 17mm versus No Treatment · women with known obstetric outcomes

It is very uncertain whether the intervention changes PTB (< 37w) ‐ PTB (<37w) ‐ Depth ≥15 to 17mm versus No Treatment (very low certainty).

1 finding from 1 review

Intervention not reported

PTB (< 37 w) ‐ PTB (< 37 w) ‐ Depth ≥ 20 mm versus No Treatment · women with known obstetric outcomes

It is very uncertain whether the intervention changes PTB (< 37 w) ‐ PTB (< 37 w) ‐ Depth ≥ 20 mm versus No Treatment (very low certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality at 2 days ‐ immediate treatment · patients with acute myocardial infarction or stroke1

It is very uncertain whether the intervention changes all‐cause mortality at 2 days ‐ immediate treatment (very low certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality at 10 days ‐ short‐term treatment · patients with acute myocardial infarction or stroke1

It is very uncertain whether the intervention changes all‐cause mortality at 10 days ‐ short‐term treatment (very low certainty).

1 finding from 1 review

PHASE SPECIFIC TREATMENT (RISPERIDONE + CBT) + SPECIALISED TEAM vs SPECIALISED TEAM

Progression to psychosis ‐ by 12 months · people with psychosis

PHASE SPECIFIC TREATMENT (RISPERIDONE + CBT) + SPECIALISED TEAM probably leads to lower progression to psychosis ‐ by 6 months compared with SPECIALISED TEAM (moderate certainty).

2 findings from 1 review

Summary of findings table ‐ CBT without antipsychotics vs no specific treatment

Leaving the study early/ loss to · schizophrenia

Summary of findings table ‐ CBT without antipsychotics showed no clear difference in leaving the study early ‐ for any reason ‐ overall acceptability… compared with no specific treatment (low certainty).

1 finding from 1 review