Cochrane · systematic review · CD010127
Perioperative nutrition for the treatment of bladder cancer by radical cystectomy
Burden, S, Billson, HA, Lal, S, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
UrologyAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
21
current version
GRADE rated
18
No studies
3
Included studies
NR
No studies 3 · 14.3%Ungraded 0 · 0%Very low 8 · 38.1%Low 10 · 47.6%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Postoperative parenteral nutrition compared to oral nutrition alone for the treatment of bladder cancer by radical cystectomy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Complications Postoperative parenteral nutrition vs oral nutrition alone | RR 1.4 [1.07, 1.82] | 1 study · 157 participants | Low Downgraded: risk of bias, imprecision |
Length of hospital stay Postoperative parenteral nutrition vs oral nutrition alone | no estimate extracted | 1 study · 157 participants | Low Downgraded: risk of bias, imprecision |
Mortality Postoperative parenteral nutrition vs oral nutrition alone | RR 1.12 [0.07, 17.62] | 1 study · 157 participants | Very low Downgraded: risk of bias, imprecision |
Immunonutrition compared to standard nutritional supplements for the treatment of bladder cancer by radical cystectomy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Complications Immunonutrition vs standard nutritional supplements | RR 0.31 [0.08, 1.23] | 1 study · 29 participants | Low Downgraded: imprecision |
Length of hospital stay Immunonutrition vs standard nutritional supplements | no estimate extracted | 1 study · 29 participants | Low Downgraded: imprecision |
Mortality Immunonutrition vs standard nutritional supplements | no estimate extracted | 1 study · 29 participants | Low Downgraded: imprecision |
Preoperative oral nutritional support compared to normal diet for the treatment of bladder cancer by radical cystectomy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Complications Preoperative oral nutritional support vs normal diet | RR 0.89 [0.18, 4.51] | 1 study · 28 participants | Very low Downgraded: risk of bias, imprecision |
Length of hospital stay – not measured Preoperative oral nutritional support vs normal diet | no estimate extracted | NR | No studies |
Mortality Preoperative oral nutritional support vs normal diet | no estimate extracted | 1 study · 28 participants | Very low Downgraded: risk of bias, imprecision |
Early postoperative feeding compared to standard management for the treatment of bladder cancer by radical cystectomy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Complications Early postoperative feeding vs standard management | RR 1.14 [0.85, 1.53] | 1 study · 102 participants | Very low Downgraded: risk of bias, imprecision |
Length of hospital stay Early postoperative feeding vs standard management | no estimate extracted | 1 study · 102 participants | Low Downgraded: risk of bias, imprecision |
Mortality Early postoperative feeding vs standard management | RR 0.52 [0.1, 2.71] | 1 study · 102 participants | Low Downgraded: risk of bias, imprecision |
Amino acid solution, alone or in combination with dextrose compared to dextrose solution for the treatment of bladder cancer by radical cystectomy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Complications Amino acid solution, alone or in combination with dextrose vs dextrose solution | RR 0.77 [0.32, 1.82] | 2 studies · 104 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Length of hospital stay Amino acid solution, alone or in combination with dextrose vs dextrose solution | no estimate extracted | 1 study · 44 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Mortality Amino acid solution, alone or in combination with dextrose vs dextrose solution | no estimate extracted | 1 study · 60 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Branch chain amino acids compared to dextrose for the treatment of bladder cancer by radical cystectomy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Complications Branch chain amino acids vs dextrose | no estimate extracted | 1 study · 19 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Length of hospital stay – not assessed Branch chain amino acids vs dextrose | no estimate extracted | NR | No studies |
Mortality – not assessed Branch chain amino acids vs dextrose | no estimate extracted | NR | No studies |
Oral nutritional supplements compared to multivitamin and mineral supplement for treatment of bladder cancer by radical cystectomy
Population: treatment of bladder cancer by radical cystectomy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Complications Oral nutritional supplements vs multivitamin and mineral supplement | RR 0.73 [0.47, 1.13] | 1 study · 61 participants | Low Downgraded: risk of bias, imprecision |
Length of hospital stay Oral nutritional supplements vs multivitamin and mineral supplement | no estimate extracted | 1 study · 61 participants | Low Downgraded: risk of bias, imprecision |
Mortality Oral nutritional supplements vs multivitamin and mineral supplement | RR 0.97 [0.06, 14.78] | 1 study · 61 participants | Low Downgraded: risk of bias, imprecision |