Cochrane · systematic review · CD004718
Early intervention for psychosis
Marshall, M, Rathbone, J · Cochrane Database of Systematic Reviews · 2011 · Cochrane Library
SchizophreniaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
9
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 9 · 100%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
PHASE SPECIFIC TREATMENT (RISPERIDONE + CBT) + SPECIALISED TEAM compared to SPECIALISED TEAM for psychosis
Population: patients with psychosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Leaving the study early ‐ by 12 months PHASE SPECIFIC TREATMENT (RISPERIDONE + CBT) + SPECIALISED TEAM vs SPECIALISED TEAM | no estimate extracted | 1 study · 59 participants | Moderate Downgraded: risk of bias |
Progression to psychosis ‐ by 6 months PHASE SPECIFIC TREATMENT (RISPERIDONE + CBT) + SPECIALISED TEAM vs SPECIALISED TEAM | RR 0.27 [0.08, 0.89] | 1 study · 59 participants | Moderate Downgraded: risk of bias |
Progression to psychosis ‐ by 12 months PHASE SPECIFIC TREATMENT (RISPERIDONE + CBT) + SPECIALISED TEAM vs SPECIALISED TEAM | RR 0.54 [0.23, 1.3] | 1 study · 59 participants | Moderate Downgraded: risk of bias |
SPECIALISED TEAM compared to STANDARD CARE for psychosis
Population: patients with psychosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Compliance with treatment ‐ treatment stopped in spite of need ‐ by one year SPECIALISED TEAM vs STANDARD CARE | RR 0.2 [0.1, 0.42] | 1 study · 507 participants | Moderate Downgraded: risk of bias |
Compliance with treatment ‐ treatment stopped in spite of need ‐ by two years SPECIALISED TEAM vs STANDARD CARE | RR 0.66 [0.29, 1.5] | 1 study · 436 participants | Moderate Downgraded: risk of bias |
Service use: 1. Average mean number of days per month in hospital ‐ by 5 years SPECIALISED TEAM vs STANDARD CARE | no estimate extracted | 1 study · 547 participants | Moderate Downgraded: risk of bias |
Service use: 2. Not hospitalised ‐ by five years SPECIALISED TEAM vs STANDARD CARE | RR 1.05 [0.9, 1.22] | 1 study · 547 participants | Moderate Downgraded: risk of bias |
Social outcomes: 1. Not living independently ‐ by 5 years SPECIALISED TEAM vs STANDARD CARE | RR 0.42 [0.21, 0.83] | 1 study · 547 participants | Moderate Downgraded: risk of bias |
Social outcomes: 2. Not working or in education ‐ by 5 years SPECIALISED TEAM vs STANDARD CARE | RR 1.06 [0.92, 1.23] | 1 study · 547 participants | Moderate Downgraded: risk of bias |