Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

920 questions · 964 findings · 153 reviews

No studies found 215 · 22.3%GRADE not reported 85 · 8.8%Very low 241 · 25%Low 260 · 27%Moderate 135 · 14%High 28 · 2.9%

Obesity (Unclassified) vs Normal Weight or Non‐Obese

Caries experience (mean DMFT) · Brazilian children in primary dentition (BMI classified by CDC 2000 growth charts)

Obesity may make little or no difference to caries experience (dmft) in the primary dentition (very low certainty).

1 finding from 1 review

Summary of findings table – disulfiram vs placebo or no pharmacological treatment

Continuous abstinence from cocaine (number of participants who had achieved and maintained abstinence for at least three weeks at the end of treatment) · patients with the treatment of cocaine dependence

Summary of findings table – disulfiram showed no clear difference in continuous abstinence from cocaine (number of participants who had… compared with placebo or no pharmacological treatment (low certainty).

1 finding from 1 review

Psychosocial interventions vs treatment

Number of continuously abstinent women ‐ total · stopping or reducing alcohol consumption during pregnancy

Summary of findings table ‐ Any psychosocial intervention may leads to higher number of continuously abstinent women ‐ total compared with treatment (low certainty).

1 finding from 1 review

Obesity (Unclassified) vs Normal Weight or Non‐Obese

Caries experience (mean DMFT) · Brazilian children/adolescents in permanent dentition (BMI classified by CDC 2000 growth charts)

Normal-weight adolescents may have higher caries experience (DMFT) than obese peers in the permanent dentition, but the evidence is very uncertain (very low certainty).

1 finding from 1 review

Malocclusion vs No malocclusion

Oral health-related quality of life · Indian children, adolescents and adults

One GOHAI study found no significant difference in OHRQoL by malocclusion status; ungraded.

2 findings from 1 review

Bruxism vs No bruxism

Oral health-related quality of life · Indian children and adults

Two studies found bruxers have poorer OHRQoL than non-bruxers; narrative, ungraded.

1 finding from 1 review

Periodontal disease assessed by loss of attachment (LOA / clinical attachment loss) vs Individuals without periodontal disease (by LOA)

Oral health-related quality of life · Indian adults and elderly (general, police, teachers, institutionalised)

No difference in OHRQoL was seen between groups for periodontal disease by LOA on OHIP-14/OIDP (pooled SMD -0.04, CI includes 0); ungraded.

2 findings from 1 review

Gingivitis (assessed by gingival index or WHO criteria) vs Individuals without gingivitis

Oral health-related quality of life · Indians

Continuous analyses (GOHAI, OHIP-14) of gingivitis and OHRQoL were inconsistent and mostly non-significant; ungraded.

1 finding from 1 review

Periodontal disease assessed by Community Periodontal Index (CPI) vs Individuals without periodontal disease (by CPI)

Oral health-related quality of life · Indian adults and elderly (general, police, teachers, institutionalised)

No difference in OHRQoL was seen between groups for periodontal disease by CPI on OHIP-14/OIDP (pooled SMD -0.18, CI includes 0); ungraded.

2 findings from 1 review

Dental caries vs Caries-free controls

Oral health-related quality of life · Indians

Three studies using GOHAI found dental caries associated with poorer OHRQoL (P<0.05); narrative, ungraded.

2 findings from 1 review

Edentulism (complete or partial missing teeth) vs Individuals without edentulism

Oral health-related quality of life · Indian elderly

Continuous (GOHAI/WHOQoL) evidence on edentulism and OHRQoL was inconsistent across two studies; ungraded.

2 findings from 1 review

Dental caries vs Caries-free controls

Oral health-related quality of life · Indian children aged 3-5 years

In children aged 3-5 years, early childhood caries was significantly associated with poorer OHRQoL (narrative; 3 studies); ungraded.

1 finding from 1 review

Dental fluorosis (assessed by TFI or WHO criteria) vs Individuals without dental fluorosis

Oral health-related quality of life · Indian children and young adults

Two studies found dental fluorosis significantly associated with poorer OHRQoL; narrative, ungraded.

1 finding from 1 review