What do systematic reviews say?

Probiotics vs control

• Probiotics for preventing ventilator‐associated pneumonia 2014 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 396 participants
  Very low

Probiotics vs control

• Probiotics for preventing ventilator‐associated pneumonia 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 203 participants
  Very low

Cognitive training combined with other neuropsychological rehabilitation methods vs control

Cognitive training combined with other neuropsychological… showed no clear difference in everyday cognitive performance/patient's report compared with any control (low certainty).

• Neuropsychological rehabilitation for multiple sclerosis 2014 · Cochrane Headline outcomes only
  SMD 0.1
  4 studies · 1011 participants
  Low

Intervention not reported

• Preoperative carbohydrate treatment for enhancing recovery after elective surgery 2014 · Cochrane Headline outcomes only
  no estimate extracted
  19 studies · 1351 participants
  Very low

Daily sedation interruption vs usual care or protocolized sedation strategies that do not include daily sedation interruption

Daily sedation interruption showed no clear difference in total duration of mechanical ventilation (days) compared with usual care or protocolized sedation strategies that do not include… (moderate certainty).

• Daily sedation interruption versus no daily sedation interruption for critically ill adult patients requiring invasive… 2014 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 1282 participants
  Moderate

Daily sedation interruption vs usual care or protocolized sedation strategies that do not include daily sedation interruption

Daily sedation interruption showed no clear difference in ICU length of stay (days) compared with usual care or protocolized sedation strategies that do not include… (moderate certainty).

• Daily sedation interruption versus no daily sedation interruption for critically ill adult patients requiring invasive… 2014 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 1282 participants
  Moderate

Daily sedation interruption vs usual care or protocolized sedation strategies that do not include daily sedation interruption

Daily sedation interruption showed no clear difference in hospital length of stay (days) compared with usual care or protocolized sedation strategies that do not include… (moderate certainty).

• Daily sedation interruption versus no daily sedation interruption for critically ill adult patients requiring invasive… 2014 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 1232 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in ICU length of stay (days) (moderate certainty).

• Automated versus non‐automated weaning for reducing the duration of mechanical ventilation for critically ill adults… 2014 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 1339 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in hospital length of stay (days) (high certainty).

• Automated versus non‐automated weaning for reducing the duration of mechanical ventilation for critically ill adults… 2014 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 749 participants
  High

Intervention not reported

The intervention showed no clear difference in mortality (ICU, hospital) (days) (high certainty).

• Automated versus non‐automated weaning for reducing the duration of mechanical ventilation for critically ill adults… 2014 · Cochrane Headline outcomes only
  no estimate extracted
  12 studies · 1128 participants
  High

Intervention not reported

The intervention showed no clear difference in oedema ‐ Day 1 Scale 1 to 4 (low certainty).

• Perioperative corticosteroids for preventing complications following facial plastic surgery 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 60 participants
  Low

Intervention not reported

The intervention showed no clear difference in ecchymosis ‐ Day 1 Scale 1 to 4 (low certainty).

• Perioperative corticosteroids for preventing complications following facial plastic surgery 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 60 participants
  Low

Melatonin vs placebo

• Pharmacological interventions for sleepiness and sleep disturbances caused by shift work 2014 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 263 participants
  Low

Melatonin vs placebo

• Pharmacological interventions for sleepiness and sleep disturbances caused by shift work 2014 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 74 participants
  Low

BRIEF FAMILY INTERVENTION vs usual care

The review found no eligible studies for this question.

• Family intervention (brief) for schizophrenia 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

• Interventions for treating inadvertent postoperative hypothermia 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 130 participants
  Low

Glutamine‐supplemented nutrition vs non‐supplemented nutrition

• Glutamine supplementation for critically ill adults 2014 · Cochrane Headline outcomes only
  no estimate extracted
  14 studies · 1297 participants
  Moderate

Job loss prevention vs control intervention

• Non‐pharmacological interventions for preventing job loss in workers with inflammatory arthritis 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 32 participants
  Very low

Intervention not reported

• Rosuvastatin for lowering lipids 2014 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 450 participants
  Low

Intervention not reported

• Rosuvastatin for lowering lipids 2014 · Cochrane Headline outcomes only
  no estimate extracted
  25 studies · 2602 participants
  High