Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,454 questions · 3,562 findings · 816 reviews · Headline outcomes only

No studies found 538 · 15.1%GRADE not reported 239 · 6.7%Very low 933 · 26.2%Low 1,041 · 29.2%Moderate 612 · 17.2%High 199 · 5.6%

TCu 220C vs Copper 7

Discontinuation due to pregnancy (750 days) · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to pregnancy (750 days) compared with copper 7 (moderate certainty).

1 finding from 1 review

TCu 220C vs Copper 7

Discontinuation due to expulsion (750 days) · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to expulsion (750 days) compared with copper 7 (moderate certainty).

1 finding from 1 review

TCu 220C vs Lippes Loop

Discontinuation due to perforation · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to perforation (750 days) Tietze‐Potter gross… compared with lippes Loop (moderate certainty).

1 finding from 1 review

TCu 220C vs Lippes Loop

Discontinuation due to pelvic inflammation · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to pelvic inflammatory disease (750 days) compared with lippes Loop (moderate certainty).

1 finding from 1 review

TCu 220C vs Lippes Loop

Discontinuation due to pregnancy (750 days) · patients with Immediate insertion Post abortion

TCu 220C probably leads to lower discontinuation rate due to pregnancy (750days) compared with lippes Loop (moderate certainty).

1 finding from 1 review

TCu 220C vs Lippes Loop

Discontinuation due to expulsion (750 days) · patients with Immediate insertion Post abortion

TCu 220C probably leads to lower discontinuation rate due to expulsion (750 days) Tietze‐Potter gross… compared with lippes Loop (moderate certainty).

1 finding from 1 review

Nocturnal ventilation vs no ventilation

No improvement of daytime hypercapnia: long‐term · patients with neuromuscular and chest wall disorders and chronic hypoventilation

It is very uncertain whether nocturnal ventilation changes no improvement of daytime hypercapnia: long‐term compared with no ventilation (very low certainty).

1 finding from 1 review

Volume‐cycled ventilation vs pressure‐cycled ventilation

No improvement of daytime hypercapnia: long‐term ‐ not measured · patients with neuromuscular and chest wall disorders and chronic hypoventilation

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Days in hospital · Patients with dengue‐related shock
1 finding from 1 review

Chlorhexidine (vaginal wash or gel/cream) vs placebo or no treatment

Early onset GBS disease (sepsis and/or meningitis within the first seven days of life)) · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants

It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes early onset GBS disease (sepsis and/or meningitis within the first… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Chlorhexidine (vaginal wash or gel/cream) vs placebo or no treatment

GBS pneumonia within the first seven days of life · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants

It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes GBS pneumonia within the first seven days of life compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Chlorhexidine (vaginal wash or gel/cream) vs placebo or no treatment

Neonatal colonization with GBS within the first seven days of life · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants

It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes neonatal colonization with GBS within the first seven days of life compared with placebo or no treatment (very low certainty).

1 finding from 1 review