Cochrane · systematic review · CD001941
Nocturnal mechanical ventilation for chronic hypoventilation in patients with neuromuscular and chest wall disorders
Annane, D, Orlikowski, D, Chevret, S · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
NeuromuscularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
5
No studies
3
Included studies
NR
No studies 3 · 37.5%Ungraded 0 · 0%Very low 5 · 62.5%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Nocturnal ventilation versus no ventilation for chronic hypoventilation in patients with neuromuscular and chest wall disorders
Population: patients with neuromuscular and chest wall disorders and chronic hypoventilation
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality at 1 year (or more) Nocturnal ventilation vs no ventilation | RR 0.62 [0.42, 0.91] | 4 studies · 99 participants | Very low Downgraded: inconsistency |
Unplanned admission to hospital Nocturnal ventilation vs no ventilation | RR 0.25 [0.08, 0.82] | 2 studies · 38 participants | Very low Downgraded: inconsistency |
No improvement of hypoventilation symptoms: long‐term Nocturnal ventilation vs no ventilation | RR 0.43 [0.18, 1.03] | 3 studies · 51 participants | Very low Downgraded: inconsistency |
No improvement of daytime hypercapnia: long‐term Nocturnal ventilation vs no ventilation | RR 0.59 [0.41, 0.86] | 3 studies · 58 participants | Very low Downgraded: inconsistency |
Volume‐cycled ventilation versus pressure‐cycled ventilation for chronic hypoventilation in patients with neuromuscular and chest wall disorders
Population: patients with neuromuscular and chest wall disorders and chronic hypoventilation
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality at 1 year (or more) Not measured ‐ data reported for mortality at 3 months Volume‐cycled ventilation vs pressure‐cycled ventilation | RR 1.29 [0.1, 17.14] | 1 study · 16 participants | Very low Downgraded: imprecision |
Unplanned admission to hospital ‐ not measured Volume‐cycled ventilation vs pressure‐cycled ventilation | no estimate extracted | NR | No studies |
No improvement of hypoventilation symptoms: long‐term ‐ not measured Volume‐cycled ventilation vs pressure‐cycled ventilation | no estimate extracted | NR | No studies |
No improvement of daytime hypercapnia: long‐term ‐ not measured Volume‐cycled ventilation vs pressure‐cycled ventilation | no estimate extracted | NR | No studies |