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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,000 questions in 69 reviews · Urology

current versions
No studies 196 · 19.6%Ungraded 33 · 3.3%Very low 198 · 19.8%Low 354 · 35.4%Moderate 206 · 20.6%High 13 · 1.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
URS with stent placement vs URS with no stent placement
Postoperative pain day 1 to day 3
Ureteral stent versus no ureteral stent for ureteroscopy in the management of renal and ureteral calculi (2019) · Cochrane
no estimate extracted8 studies · 683 participantsLow
URS with stent placement vs URS with no stent placement
Postoperative pain day 4 to day 30
Ureteral stent versus no ureteral stent for ureteroscopy in the management of renal and ureteral calculi (2019) · Cochrane
no estimate extracted8 studies · 903 participantsVery low
URS with stent placement vs URS with no stent placement
Secondary interventions
Ureteral stent versus no ureteral stent for ureteroscopy in the management of renal and ureteral calculi (2019) · Cochrane
RR 1.15 [0.39, 3.33]10 studies · 1435 participantsLow
URS with stent placement vs URS with no stent placement
Narcotic requirement
Ureteral stent versus no ureteral stent for ureteroscopy in the management of renal and ureteral calculi (2019) · Cochrane
RR 0.8 [0.48, 1.36]7 studies · 830 participantsVery low
URS with stent placement vs URS with no stent placement
UTI (positive urine culture as well as symptoms) up to 90 days
Ureteral stent versus no ureteral stent for ureteroscopy in the management of renal and ureteral calculi (2019) · Cochrane
RR 0.94 [0.59, 1.51]10 studies · 1207 participantsModerate
URS with stent placement vs URS with no stent placement
Ureteral stricture up to 90 days
Ureteral stent versus no ureteral stent for ureteroscopy in the management of renal and ureteral calculi (2019) · Cochrane
RR 0.58 [0.23, 1.47]14 studies · 1625 participantsVery low
URS with stent placement vs URS with no stent placement
Hospital admission
Ureteral stent versus no ureteral stent for ureteroscopy in the management of renal and ureteral calculi (2019) · Cochrane
RR 0.7 [0.32, 1.55]13 studies · 1647 participantsVery low
PUL vs TURP
Urological symptom scores
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 72 participantsLow
PUL vs TURP
Retreatment
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
RR 2.39 [0.51, 11.1]1 study · 79 participantsVery low
PUL vs TURP
Erectile function
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 57 participantsModerate
PUL vs TURP
Ejaculatory function
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 56 participantsLow
PUL vs sham
Urological symptom scores
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 206 participantsLow
PUL vs sham
Quality of life
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 206 participantsModerate
PUL vs sham
Major adverse events
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
RR 3.3 [0.41, 26.28]1 study · 206 participantsVery low
PUL vs sham
Retreatment
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 206 participantsLow
PUL vs sham
Erectile function
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 197 participantsModerate
PUL vs sham
Ejaculatory function
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 144 participantsModerate
PUL vs TURP
Quality of life
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 72 participantsLow
PUL vs TURP
Major adverse events
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
RR 0.64 [0.18, 2.19]1 study · 79 participantsVery low
PUL vs TURP
Retreatment
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
RR 1.19 [0.21, 6.75]1 study · 79 participantsVery low
PUL vs TURP
Erectile function
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 59 participantsModerate
PUL vs TURP
Ejaculatory function
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 59 participantsModerate
PUL vs TURP
Urological symptom scores
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 69 participantsLow
PUL vs TURP
Quality of life
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 69 participantsLow
PUL vs TURP
Major adverse events
Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extractedNRNo studies
Aquablation vs transurethral resection of the prostate
Urologic symptom scores · men with benign prostatic hyperplasia (BPH)
Aquablation of the prostate for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 174 participantsModerate
Aquablation vs transurethral resection of the prostate
Quality of life · men with benign prostatic hyperplasia (BPH)
Aquablation of the prostate for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 174 participantsLow
Aquablation vs transurethral resection of the prostate
Major adverse events · men with benign prostatic hyperplasia (BPH)
Aquablation of the prostate for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
RR 0.84 [0.31, 2.26]1 study · 181 participantsVery low
Aquablation vs transurethral resection of the prostate
Retreatment · men with benign prostatic hyperplasia (BPH)
Aquablation of the prostate for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
RR 1.68 [0.18, 15.83]1 study · 181 participantsVery low
Aquablation vs transurethral resection of the prostate
Erectile function (sexually active men only) · men with benign prostatic hyperplasia (BPH)
Aquablation of the prostate for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 64 participantsVery low
Aquablation vs transurethral resection of the prostate
Ejaculatory function (sexually active men only) · men with benign prostatic hyperplasia (BPH)
Aquablation of the prostate for the treatment of lower urinary tract symptoms in men with benign prostatic… (2019) · Cochrane
no estimate extracted1 study · 121 participantsVery low
Single‐dose intravesical chemotherapy instillation vs placebo or observation after nephroureterectomy
Time to bladder cancer recurrence (absolute effect size estimates based on recurrence rate at 12 months)
Single‐dose intravesical chemotherapy after nephroureterectomy for upper tract urothelial carcinoma (2019) · Cochrane
HR 0.51 [0.32, 0.82]2 studies · 311 participantsLow
Single‐dose intravesical chemotherapy instillation vs placebo or observation after nephroureterectomy
Time to death from UTUC5
Single‐dose intravesical chemotherapy after nephroureterectomy for upper tract urothelial carcinoma (2019) · Cochrane
no estimate extractedNRNo studies
Single‐dose intravesical chemotherapy instillation vs placebo or observation after nephroureterectomy
Serious adverse events
Single‐dose intravesical chemotherapy after nephroureterectomy for upper tract urothelial carcinoma (2019) · Cochrane
no estimate extracted2 studies · 311 participantsVery low
Single‐dose intravesical chemotherapy instillation vs placebo or observation after nephroureterectomy
Time to death from any cause5
Single‐dose intravesical chemotherapy after nephroureterectomy for upper tract urothelial carcinoma (2019) · Cochrane
no estimate extractedNRNo studies
Single‐dose intravesical chemotherapy instillation vs placebo or observation after nephroureterectomy
Minor adverse events
Single‐dose intravesical chemotherapy after nephroureterectomy for upper tract urothelial carcinoma (2019) · Cochrane
no estimate extracted1 study · 72 participantsVery low
Single‐dose intravesical chemotherapy instillation vs placebo or observation after nephroureterectomy
Disease‐specific quality of life5
Single‐dose intravesical chemotherapy after nephroureterectomy for upper tract urothelial carcinoma (2019) · Cochrane
no estimate extractedNRNo studies
Impact of extended vs standard lymph node dissection on overall survival among patients with urothelial cancer of the bladder
Time to death from any cause (absolute effect size estimates based on death rate at 5 years) · Partcipants with bladder cancer undergoing radical cystectomy (male n = 314, female n = 87; age (interquartile range)…
Extended versus standard lymph node dissection for urothelial carcinoma of the bladder in patients… (2019) · Cochrane
HR 0.78 [0.57, 1.07]1 study · 401 participantsLow
Impact of extended vs standard lymph node dissection on overall survival among patients with urothelial cancer of the bladder
Time to death from bladder cancer (absolute effect size estimates based on death rate at 5 years) · Partcipants with bladder cancer undergoing radical cystectomy (male n = 314, female n = 87; age (interquartile range)…
Extended versus standard lymph node dissection for urothelial carcinoma of the bladder in patients… (2019) · Cochrane
HR 0.7 [0.45, 1.07]1 study · 401 participantsLow
Impact of extended vs standard lymph node dissection on overall survival among patients with urothelial cancer of the bladder
Clavien‐Dindo grade ≥ 3 complications · Partcipants with bladder cancer undergoing radical cystectomy (male n = 314, female n = 87; age (interquartile range)…
Extended versus standard lymph node dissection for urothelial carcinoma of the bladder in patients… (2019) · Cochrane
RR 1.13 [0.84, 1.52]1 study · 401 participantsVery low
Impact of extended vs standard lymph node dissection on overall survival among patients with urothelial cancer of the bladder
Time to recurrence (absolute effect size estimates based on recurrence rate at 5 years) · Partcipants with bladder cancer undergoing radical cystectomy (male n = 314, female n = 87; age (interquartile range)…
Extended versus standard lymph node dissection for urothelial carcinoma of the bladder in patients… (2019) · Cochrane
HR 0.84 [0.58, 1.22]1 study · 401 participantsVery low
Impact of extended vs standard lymph node dissection on overall survival among patients with urothelial cancer of the bladder
Clavien‐Dindo grade ≤ 2 complications8 · Partcipants with bladder cancer undergoing radical cystectomy (male n = 314, female n = 87; age (interquartile range)…
Extended versus standard lymph node dissection for urothelial carcinoma of the bladder in patients… (2019) · Cochrane
RR 0.94 [0.74, 1.19]1 study · 401 participantsVery low
Impact of extended vs standard lymph node dissection on overall survival among patients with urothelial cancer of the bladder
Disease‐specific quality of life9 · Partcipants with bladder cancer undergoing radical cystectomy (male n = 314, female n = 87; age (interquartile range)…
Extended versus standard lymph node dissection for urothelial carcinoma of the bladder in patients… (2019) · Cochrane
no estimate extractedNRNo studies
Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)
Time to death from prostate cancer (absolute effects: disease‐specific mortality)
Primary cryotherapy for localised or locally advanced prostate cancer (2018) · Cochrane
HR 1 [0.11, 9.45]2 studies · 293 participantsVery low
Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)
Quality of life ‐ urinary function
Primary cryotherapy for localised or locally advanced prostate cancer (2018) · Cochrane
no estimate extracted1 study · 195 participantsVery low
Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)
Quality of life ‐ bowel function
Primary cryotherapy for localised or locally advanced prostate cancer (2018) · Cochrane
no estimate extracted1 study · 195 participantsVery low
Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)
Quality of life ‐ sexual function
Primary cryotherapy for localised or locally advanced prostate cancer (2018) · Cochrane
no estimate extracted1 study · 195 participantsVery low
Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)
Major adverse events
Primary cryotherapy for localised or locally advanced prostate cancer (2018) · Cochrane
RR 0.91 [0.47, 1.78]2 studies · 293 participantsVery low
Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)
Time to death from any cause (absolute effects: overall mortality)
Primary cryotherapy for localised or locally advanced prostate cancer (2018) · Cochrane
HR 0.99 [0.05, 18.79]2 studies · 293 participantsVery low
Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)
Secondary interventions for treatment failure ‐ not reported
Primary cryotherapy for localised or locally advanced prostate cancer (2018) · Cochrane
no estimate extractedNRNo studies