Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,149 questions · 1,211 findings · 179 reviews

No studies found 175 · 14.5%GRADE not reported 86 · 7.1%Very low 286 · 23.6%Low 341 · 28.2%Moderate 254 · 21%High 69 · 5.7%

Summary of findings: NBAS or NBO vs control

Caregiver knowledge (related to infants' physical capacities, including reflexes and senses) Assessed at postintervention, using multiple choice factual questions; higher scores indicate better outcome · caregiver‐infant dyads
1 finding from 1 review

ART with seminal plasma vs standard ART (IVF, ICSI, and frozen embryo transfer)

Multiple pregnancy · Women undergoing ART (IVF, ICSI, or frozen embryo transfer)

ART with seminal plasma showed no clear difference in multiple pregnancy compared with standard ART (IVF, ICSI, and frozen embryo transfer) (low certainty).

1 finding from 1 review

Myo‐inositol vs clomiphene

Adverse event ‐ multiple pregnancy · subfertile women with polycystic ovary syndrome

It is very uncertain whether myo‐inositol changes adverse event ‐ multiple pregnancy compared with an ovulation induction agent (clomiphene) (very low certainty).

1 finding from 1 review

Closed‐system transfer device plus safe handling vs safe handling alone

Irinotecan, docetaxel, paclitaxel, vinorelbine, ganciclovir, epirubicin, multiple drugsϯ · healthcare staff who handle infusional hazardous drugs

It is very uncertain whether closed‐system transfer device plus safe handling changes irinotecan, docetaxel, paclitaxel, vinorelbine, ganciclovir,… compared with safe handling alone (very low certainty).

1 finding from 1 review

Repeated lumbar or ventricular punctures vs conservative treatment

Multiple disability in survivors · preterm infants less than three months of age with either: a) IVH demonstrated by ultrasound or computed tomography (CT) scan; or b)…

Repeated lumbar or ventricular punctures showed no clear difference in multiple disability in survivors compared with conservative treatment (high certainty).

1 finding from 1 review