Cochrane · systematic review · CD010001

Vasodilators for women undergoing fertility treatment

Gutarra‐Vilchez, RB, Bonfill Cosp, X, Glujovsky, D, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Gynaecology and Fertility2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 4 · 57.1%Moderate 2 · 28.6%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Vasodilator compared to placebo or no treatment for women undergoing fertility treatment

Population: women undergoing fertility treatment
7 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth
Vasodilator vs placebo or no treatment
RR 1.18 [0.83, 1.69]3 studies · 350 participantsModerate
Downgraded: imprecision
Vasodilator side effects
Vasodilator vs placebo or no treatment
RR 2.35 [1.51, 3.66]4 studies · 418 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Clinical pregnancy
Vasodilator vs placebo or no treatment
RR 1.45 [1.19, 1.77]11 studies · 1054 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Thickened endometrium
Vasodilator vs placebo or no treatment
no estimate extracted5 studies · 477 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Multiple gestation or birth
Vasodilator vs placebo or no treatment
RR 1.15 [0.55, 2.42]3 studies · 370 participantsLow
Downgraded: imprecision
Spontaneous miscarriage
Vasodilator vs placebo or no treatment
RR 0.83 [0.37, 1.86]3 studies · 350 participantsLow
Downgraded: imprecision
Ectopic pregnancy
Vasodilator vs placebo or no treatment
RR 1.48 [0.25, 8.69]2 studies · 250 participantsLow
Downgraded: imprecision