Cochrane · systematic review · CD000216
Repeated lumbar or ventricular punctures in newborns with intraventricular haemorrhage
Whitelaw, A, Lee‐Kelland, R · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 28.6%Moderate 2 · 28.6%High 3 · 42.9%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Repeated lumbar or ventricular punctures compared to conservative treatment in newborns with intraventricular haemorrhage
Population: preterm infants less than three months of age with either: a) IVH demonstrated by ultrasound or computed tomography (CT) scan; or b) infants with IVH followed by progressive ventricular dilatation.
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Hydrocephalus shunt Repeated lumbar or ventricular punctures vs conservative treatment | RR 0.96 [0.73, 1.26] | 3 studies · 233 participants | Moderate Downgraded: risk of bias |
Death Repeated lumbar or ventricular punctures vs conservative treatment | RR 0.88 [0.53, 1.44] | 4 studies · 280 participants | Low Downgraded: risk of bias, imprecision |
Major disability in survivors Repeated lumbar or ventricular punctures vs conservative treatment | RR 0.98 [0.81, 1.18] | 2 studies · 141 participants | High |
Multiple disability in survivors Repeated lumbar or ventricular punctures vs conservative treatment | RR 0.9 [0.66, 1.24] | 2 studies · 141 participants | High |
Death or disability Repeated lumbar or ventricular punctures vs conservative treatment | RR 0.99 [0.86, 1.14] | 2 studies · 180 participants | High |
Death or shunt Repeated lumbar or ventricular punctures vs conservative treatment | RR 0.91 [0.75, 1.11] | 3 studies · 233 participants | Moderate Downgraded: risk of bias |
Infection of CSF presurgery Repeated lumbar or ventricular punctures vs conservative treatment | RR 1.73 [0.53, 5.67] | 2 studies · 195 participants | Low Downgraded: imprecision, inconsistency |