Depression score SCL‐90‐R depression sub‐scale (13 items); HAM‐D. Scale from: 0 to 84 (HAM‐D) or 52 (SCL‐90‐R depression sub‐scale). · patients with depression
1 finding from 1 review
Intervention not reported
Achieved recovery according to predetermined criteria (no longer meeting criteria for depression on K‐SADS or meeting a priori criteria for response on a depression checklist, assessed between 4 and 10 weeks of onset of treatment) · children and adolescents with depression
The intervention showed no clear difference in achieved recovery according to predetermined criteria (no longer… (low certainty).
1 finding from 1 review
Intervention not reported
Change in depression checklist scores (BID, CDI, CDRS, DACL or HAM‐D from baseline to between 2 and 10 weeks) · children and adolescents with depression
1 finding from 1 review
Effect on later sexual function · people with antidepressant‐induced sexual dysfunction
Sildenafil probably leads to lower clinical Global Impression ‐Sexual Function not "much/very much… compared with placebo (moderate certainty).
1 finding from 1 review
Endpoint scale total scores (150 mg twice daily dose) (Scales of sexual functioning. As studies used different scales to assess sexual functioning, differences are expressed as standardised mean differences (SMD)) · people with antidepressant‐induced sexual dysfunction
1 finding from 1 review
Symptoms of depression (long‐term) different scales · depression in adults
2 findings from 1 review
Symptoms of depression · depression in adults
1 finding from 1 review
Symptoms of depression · depression in adults
1 finding from 1 review
Symptoms of depression · depression in adults
1 finding from 1 review
Depression severity · patients with depression
1 finding from 1 review
Depression severity · patients with depression
1 finding from 1 review
Depression severity · patients with depression
1 finding from 1 review
Depression levels at post‐treatment (HAM‐D) · patients with depression
1 finding from 1 review
Depression levels at · patients with depression
1 finding from 1 review
Depression levels at post‐treatment · depression
1 finding from 1 review
Response rates Number of participants showing a reduction of at least 50% on the Hamilton Depression Rating Scale for Depression, the Montgomery‐Asberg Depression Rating Scale or any other depression scale · patients with major depression
It is very uncertain whether agomelatine changes response rates Number of participants showing a reduction of at… compared with SSRI (very low certainty).
1 finding from 1 review
Remission · patients with major depression
It is very uncertain whether agomelatine changes remission rates The number of participants who achieved remission as… compared with SSRI (very low certainty).
1 finding from 1 review
Response rates Number of participants showing a reduction of at least 50% on the Hamilton Depression Rating Scale for Depression, the Montgomery‐Asberg Depression Rating Scale or any other depression scale · patients with major depression
It is very uncertain whether agomelatine changes response rates Number of participants showing a reduction of at… compared with SNRI (very low certainty).
1 finding from 1 review
Remission · patients with major depression
It is very uncertain whether agomelatine changes remission rates The number of participants who achieved remission as… compared with SNRI (very low certainty).
1 finding from 1 review
Response rates Number of participants showing a reduction of at least 50% on the Hamilton Depression Rating Scale for Depression, the Montgomery‐Asberg Depression Rating Scale or any other depression scale · adults with Major Depressive Disorder
Amitriptyline probably leads to higher response to treatment At least 50% reduction of a depression scale… compared with placebo (moderate certainty).
1 finding from 1 review