Postoperative wound or systemic infection · participants undergoing surgery
Dexamethasone showed no clear difference in postoperative wound or systemic infection compared with control (moderate certainty).
1 finding from 1 review
Delayed wound healing · participants undergoing surgery
Dexamethasone showed no clear difference in delayed wound healing compared with control (low certainty).
1 finding from 1 review
Glycaemic response ‐ change from baseline to 2 to 12 hours postoperatively in patients without diabetes · participants undergoing surgery
1 finding from 1 review
Glycaemic response ‐ change from baseline to 10 to 24 hours after surgery in patients with diabetes · participants undergoing surgery
1 finding from 1 review
Mortality within the longest · adults undergoing non‐cardiac surgery
Continuation showed no clear difference in all‐cause mortality (at longest compared with discontinuation of antiplatelet therapy (low certainty).
1 finding from 1 review
All‐cause mortality (up to 30 days) · adults undergoing non‐cardiac surgery
Continuation showed no clear difference in all‐cause mortality (up to 30 days) compared with discontinuation of antiplatelet therapy (low certainty).
1 finding from 1 review
Blood loss requiring transfusion of blood products (intraoperatively and postoperatively) · adults undergoing non‐cardiac surgery
Continuation showed no clear difference in blood loss requiring transfusion of blood products (intraoperatively… compared with discontinuation of antiplatelet therapy (moderate certainty).
1 finding from 1 review
Blood loss requiring further surgery (intraoperatively and postoperatively) · adults undergoing non‐cardiac surgery
Continuation showed no clear difference in blood loss requiring further surgery (intraoperatively and… compared with discontinuation of antiplatelet therapy (low certainty).
1 finding from 1 review
Ischaemic events: peripheral thrombosis, cerebral myocardial infarction (within 30 days of surgery) · adults undergoing non‐cardiac surgery
Continuation showed no clear difference in ischaemic events: peripheral thrombosis, cerebral myocardial… compared with discontinuation of antiplatelet therapy (low certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults and paediatric patients with dermal laceration
5 findings from 1 review
no estimate extracted
6 studies · 1006 participants
Low
no estimate extracted
4 studies · 530 participants
Low
no estimate extracted
6 studies · 543 participants
Low
Show 2 more findings
Anaesthetic‐related adverse effects · adults and paediatric patients with dermal laceration
Primary outcome: topical local anaesthetics led to lower anaesthetic‐related adverse effects compared with infiltrated local anaesthetics or other topical agents; GRADE not reported.
1 finding from 1 review
Death ‐ all participants · children with acute bacterial meningitis
Maintenance fluids showed no clear difference in death ‐ all participants compared with restricted fluids (low certainty).
1 finding from 1 review
Severe neurological sequelae ‐ acute (within the first 4 weeks) · children with acute bacterial meningitis
Maintenance fluids showed no clear difference in severe neurological sequelae ‐ acute (within the first 4 weeks) compared with restricted fluids (low certainty).
1 finding from 1 review
Severe neurological sequelae ‐ chronic (after the first 4 weeks) · children with acute bacterial meningitis
It is very uncertain whether maintenance fluids changes severe neurological sequelae ‐ chronic (after the first 4 weeks) compared with restricted fluids (very low certainty).
1 finding from 1 review
Intervention not reported
Mortality within the longest · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
The intervention showed no clear difference in mortality within the longest (low certainty).
1 finding from 1 review
Intervention not reported
Mortality within the longest · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
It is very uncertain whether the intervention changes mortality within the longest (very low certainty).
1 finding from 1 review
Intervention not reported
Mortality within 30 days of · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
1 finding from 1 review
Intervention not reported
Mortality within 30 days of · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
1 finding from 1 review
Intervention not reported
Surgical site infection within 30 days in trials with low risk of bias (14 days to 30 days) · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
The intervention showed no clear difference in surgical site infection within 30 days in trials with low risk of… (low certainty).
1 finding from 1 review
Intervention not reported
Surgical site infection within 30 days, irrespective of risk of bias (14 days to 30 days) · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
The intervention showed no clear difference in surgical site infection within 30 days, irrespective of risk of bias… (low certainty).
1 finding from 1 review