Question · asked by 1 review
Primary outcome: topical local anaesthetics vs infiltrated local anaesthetics or other topical agents: Anaesthetic‐related adverse effects
- Population
- adults and paediatric patients with dermal laceration
- Intervention
- Primary outcome: topical local anaesthetics
- Comparison
- infiltrated local anaesthetics or other topical agents
- Outcome
- Anaesthetic‐related adverse effects
Primary outcome: topical local anaesthetics led to lower anaesthetic‐related adverse effects compared with infiltrated local anaesthetics or other topical agents; GRADE not reported.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Primary outcome: topical local anaesthetics vs infiltrated local anaesthetics or other topical agents Anaesthetic‐related adverse effects · adults and paediatric patients with dermal laceration Primary outcome: topical local anaesthetics led to lower anaesthetic‐related adverse effects compared with infiltrated local anaesthetics or other topical agents; GRADE not reported. Topical anaesthetics for pain control during repair of dermal laceration (2017) · Cochrane Headline outcomes only | RR 0 [0, 0] | 11 studies · 1686 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Topical anaesthetics for pain control during repair of dermal laceration 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.