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Evidence found and GRADE certainty

3,801 questions · 4,079 findings · 473 reviews

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No studies found 669 · 16.4%GRADE not reported 852 · 20.9%Very low 738 · 18.1%Low 903 · 22.1%Moderate 716 · 17.6%High 201 · 4.9%

Summary of findings table ‐ LSSS intervention vs regular salt

Stroke mortality (events per 100,000 person‐years) · Adults (general population)

It is very uncertain whether summary of findings table ‐ LSSS intervention changes stroke mortality (events per 100,000 person‐years) compared with regular salt (very low certainty).

1 finding from 1 review

Atraumatic restorative treatment with GIC vs Conventional treatment

Pain during the procedure (primary analysis) · Children (3-13 years) with dentine caries in primary teeth, no pulpal involvement

The reported estimate for procedural pain with ART versus conventional treatment was inconclusive (ungraded).

1 finding from 1 review

Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls)

Probing pocket depth · Adults (general and hospital populations assessed in case-control studies)

Probing depth is significantly increased in systemic sclerosis patients (SMD 3.10) with very high heterogeneity; certainty ungraded.

3 findings from 1 review

Non-selective carious tissue removal and conventional restoration (CR) vs Selective carious tissue removal (selective excavation, SE)

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

It is very uncertain whether non-selective carious tissue removal and conventional restoration (CR) changes failure of therapy compared with selective carious tissue removal (selective excavation, SE) (very low certainty).

3 findings from 1 review

Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls)

Sites with probing depth >= 4 mm · Adults (general and hospital populations assessed in case-control studies)

Sites with probing depth >= 4 mm are significantly more frequent in SSc patients (SMD 2.07); certainty ungraded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence · General population (children and adults) in East Africa

Caries prevalence in permanent dentition (>=12 years) was 50.2% (95% CI 38.4 to 62.1); certainty not graded.

1 finding from 1 review

Dental caries assessment (WHO/clinical diagnostic criteria; caries = DMFT>0) vs None (descriptive prevalence meta-analysis)

Dental caries prevalence · General Pakistani population (all ages and both sexes; predominantly children and adolescents)

In permanent dentition, the pooled prevalence of dental caries was 57.2% (95% CI 26.3 to 85.3); ungraded.

10 findings from 1 review
Show 7 more findings

Sealing using sealant materials vs Selective carious tissue removal (selective excavation, SE)

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

It is very uncertain whether sealing using sealant materials changes failure of therapy compared with selective carious tissue removal (selective excavation, SE) (very low certainty).

1 finding from 1 review

Non-selective carious tissue removal and conventional restoration (CR) vs Stepwise carious tissue removal (SW)

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

Non-selective carious tissue removal and conventional restoration (CR) probably leads to higher failure of therapy compared with stepwise carious tissue removal (SW) (moderate certainty).

2 findings from 1 review

Selective carious tissue removal (selective excavation, SE) vs Hall Technique (sealing with a preformed metal crown)

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

It is very uncertain whether selective carious tissue removal (selective excavation, SE) changes failure of therapy compared with hall Technique (sealing with a preformed metal crown) (very low certainty).

2 findings from 1 review

Non-selective carious tissue removal and conventional restoration (CR) vs Hall Technique (sealing with a preformed metal crown)

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

Non-selective carious tissue removal and conventional restoration (CR) may leads to higher failure of therapy compared with hall Technique (sealing with a preformed metal crown) (low certainty).

1 finding from 1 review

Not applicable (single-group prevalence) vs Not applicable

Dental caries prevalence · General Pakistani population (all ages and both sexes; predominantly children and adolescents)

Fixed-effect pooled dental caries prevalence was 57.0% (95% CI 56.4% to 57.6%).

1 finding from 1 review

Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls)

Periodontitis (prevalence) · Adults (general and hospital populations assessed in case-control studies)

Periodontitis prevalence is significantly higher in systemic sclerosis patients than controls (OR 7.01); certainty ungraded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence · General population in Ethiopia (all ages, age range 6-100 years)

Caries prevalence was lowest in Addis Ababa at 34.20% (95% CI 8.42 to 59.97); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence · General population in Ethiopia (all ages, age range 6-100 years)

Caries prevalence in the Amhara region was 40.44% (95% CI 24.67 to 56.21); certainty not graded.

1 finding from 1 review

Any of the interventions (CR, SE, SW, sealing with sealant materials, Hall Technique, or NRCC) vs Each other, placebo, or no treatment

Adverse events (any type) and safety of sealant · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

The review found no eligible studies for this question.

1 finding from 1 review

Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls)

Mean number of decayed teeth (mean DT) · Adults (general and hospital populations assessed in case-control studies)

Systemic sclerosis patients have a significantly higher number of decayed teeth than controls (SMD 0.19); certainty ungraded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence · General population in Ethiopia (all ages, age range 6-100 years)

Caries prevalence in other regions (Oromia, Harar, SNNPR) was 42.90% (95% CI 24.68 to 61.12); certainty not graded.

1 finding from 1 review