Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,062 questions · 1,113 findings · 171 reviews · Headline outcomes only

No studies found 161 · 14.5%GRADE not reported 41 · 3.7%Very low 269 · 24.2%Low 321 · 28.8%Moderate 252 · 22.6%High 69 · 6.2%

Intervention not reported

Patient harms associated with patient and family involvement in escalation of care (5a) Multiple Affect Adjective Checklist total score for state anxiety (range 0‐21). Higher scores signify higher anxiety; a score of ≥ 11 indicates clinically sign... · Adults (and/or family members) with potential for acute life‐threatening illness
1 finding from 1 review

GM‐CSF‐supplemented culture media vs culture media not supplemented with GM‐CSF

Multiple gestation · women undergoing assisted reproduction

It is very uncertain whether GM‐CSF‐supplemented culture media changes multiple gestation compared with culture media not supplemented with GM‐CSF (very low certainty).

1 finding from 1 review

Intervention not reported

Disability ‒short‐term (> 2 weeks but ≤ 3 months) Disability reported using multiple scales (RMDQ and ODI). Disability scores were converted to a common 0 to 100 scale. Higher scores indicate greater disability. · lumbosacral radicular pain

The intervention showed no clear difference in disability ‒short‐term (> 2 weeks but ≤ 3 months) Disability… (moderate certainty).

1 finding from 1 review

One uterine devascularisation technique (uterine arterial embolisation) vs another uterine devascularisation technique (surgical devascularisation plus B‐Lynch)

Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) · treating primary postpartum haemorrhage

The review found no eligible studies for this question.

1 finding from 1 review

Intrauterine balloon tamponade plus normal care (misoprostol) vs normal care (misoprostol)

Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) · women diagnosed with primary PPH following vaginal birth. Women were suspected to have PPH due to clinical atony and who were quote:…

The review found no eligible studies for this question.

1 finding from 1 review

Intrauterine balloon tamponade (latex balloon inflated with air) plus cerclage and normal care vs normal care

Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) · women with PPH, due to atony, following vaginal birth at home or in hospital (Soltan 2007)

The review found no eligible studies for this question.

1 finding from 1 review

External uterine compression (all methods) plus normal care vs normal care

Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) ‐ not reported · women diagnosed with primary PPH following vaginal birth. PPH was defined as quote: "blood loss > 500mL after delivery" p 601

The review found no eligible studies for this question.

1 finding from 1 review

Bakri balloon tamponade vs haemostatic square suturing to the lower segment of the uterus (intrauterine tamponade versus another mechanical/surgical method)

Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) · women with complete placenta praevia and intractable bleeding following caesarean section
1 finding from 1 review

Bakri balloon tamponade vs condom‐loaded Foley Catheter (one intrauterine tamponade compared to another intrauterine tamponade technique)

Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) · women with primary atonic postpartum haemorrhage following vaginal delivery

The review found no eligible studies for this question.

1 finding from 1 review

Bakri balloon tamponade+traction stitch vs Bakri balloon (one intrauterine tamponade compared to another intrauterine tamponade technique)

Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) · women with primary atonic postpartum haemorrhage

The review found no eligible studies for this question.

1 finding from 1 review

Intrauterine balloon tamponade (condom‐loaded catheter) vs uterovaginal packing (intrauterine tamponade versus another intrauterine tamponade method)

Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) · Women (aged between 20 and 40) diagnosed with primary PPH following 'normal' vaginal birth and unresponsive to medical treatment (Ashraf…

The review found no eligible studies for this question.

1 finding from 1 review

Modified B‐Lynch compression suture technique vs standard B‐Lynch compression suture (one uterine compression suture technique versus another uterine compression suture technique)

Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) · women with uncontrolled atonic PPH following caesarean section, and not responding to standard care (uterine massage, ecbolics and…

The review found no eligible studies for this question.

1 finding from 1 review