Cochrane · systematic review · CD013577

Epidural corticosteroid injections for lumbosacral radicular pain

Oliveira, CB, Maher, CG, Ferreira, ML, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

Back and NeckAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 25%Low 0 · 0%Moderate 3 · 75%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings ‐ short‐term follow‐up

Population: lumbosacral radicular pain
4 questions
OutcomeEffectEvidenceStatus / GRADE
Leg pain ‒short‐term
no estimate extracted8 studies · 949 participantsModerate
Downgraded: risk of bias
Disability ‒short‐term (> 2 weeks but ≤ 3 months) Disability reported using multiple scales (RMDQ and ODI). Disability scores were converted to a common 0 to 100 scale. Higher scores indicate greater disability.
no estimate extracted12 studies · 1367 participantsModerate
Downgraded: risk of bias
Minor adverse events** ‒short‐term (> 2 weeks but ≤ 3 months) Minor adverse events provided as the proportion of patients reporting any untoward medical occurrence after an epidural injection without hospitalisations.
RR 1.14 [0.91, 1.42]8 studies · 877 participantsVery low
Downgraded: risk of bias
Major adverse events** ‒short‐term (> 2 weeks but ≤ 3 months) Major adverse events provided as the proportion of patients reporting any untoward medical occurrence after an epidural injection with hospitalizations.
no estimate extracted1 study · 160 participantsModerate
Downgraded: risk of bias