Adverse event: treatment‐related mortality · Patients with early unfavourable or advanced stage HL
Escalated BEACOPP showed no clear difference in adverse event: treatment‐related mortality compared with chemotherapy including ABVD (low certainty).
1 finding from 1 review
Treatment‐related mortality · women with early poor prognosis breast cancer
High‐dose chemotherapy leads to higher treatment‐related mortality compared with chemotherapy without bone marrow transplant or stem cell rescue (high certainty).
1 finding from 1 review
Early onset GBS disease (sepsis and/or meningitis within the first seven days of life)) · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants
It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes early onset GBS disease (sepsis and/or meningitis within the first… compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Neonatal mortality due to early‐onset GBS infection · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants
1 finding from 1 review
Acceptability (of intervention): Leaving the studies early – any reason Loss to · patients with treatment compliance for people with serious mental illness
1 finding from 1 review
Acceptability (of intervention): Leaving the studies early – any reason Loss to · patients with treatment compliance for people with serious mental illness
INFORMATION AND COMMUNICATION TECHNOLOGY (ICT) FOR PROMPTING/SUPPORT… showed no clear difference in acceptability (of intervention): Leaving the studies early – any… compared with STANDARD CARE (low certainty).
1 finding from 1 review
Hearing ‐ return to normal *Ventilation tubes versus laser myringotomy (6 to 12 months ‐ medium‐term) Adjusted for non‐independence of within‐individual measurements Assumed ICC of 0.5 № of participants: 132 (2 RCTs) · children aged 6 months to 12 years with otitis media with effusion (OME)
It is very uncertain whether early ventilation tubes changes hearing ‐ return to normal hearing Randomised by child compared with watchful waiting (treatment later if required) (very low certainty).
1 finding from 1 review
RR 0.98 [0.94, 1.03]
Studies not reported
Very low
Disease‐specific quality of life · children aged 6 months to 12 years with otitis media with effusion (OME)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Presence/persistence of OME · children aged 6 months to 12 years with otitis media with effusion (OME)
It is very uncertain whether early ventilation tubes changes presence/persistence of OME Randomised by child compared with watchful waiting (treatment later if required) (very low certainty).
1 finding from 1 review
RR 1.21 [0.84, 1.74]
Studies not reported
Very low
Adverse event: persistent perforation · children aged 6 months to 12 years with otitis media with effusion (OME)
It is very uncertain whether early ventilation tubes changes adverse event: persistent perforation compared with watchful waiting (treatment later if required) (very low certainty).
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Shoulder range of motion for abduction ‐ medium term · patients at risk for secondary upper limb lymphoedema after breast cancer treatment
1 finding from 1 review
Shoulder range of motion for forward flexion ‐ short term · patients at risk for secondary upper limb lymphoedema after breast cancer treatment
1 finding from 1 review
Shoulder range of motion for forward flexion ‐ medium term · patients at risk for secondary upper limb lymphoedema after breast cancer treatment
1 finding from 1 review
Shoulder range of motion for external rotation ‐ medium term · patients at risk for secondary upper limb lymphoedema after breast cancer treatment
1 finding from 1 review
Shoulder range of motion for internal rotation ‐ medium term · patients at risk for secondary upper limb lymphoedema after breast cancer treatment
1 finding from 1 review
Lymphoedema ‐ medium term · patients at risk for secondary upper limb lymphoedema after breast cancer treatment
It is very uncertain whether early shoulder mobilising exercises changes lymphoedema ‐ medium term compared with delayed shoulder mobilising exercises (very low certainty).
1 finding from 1 review
Shoulder range of motion for abduction ‐ short term · patients at risk for secondary upper limb lymphoedema after breast cancer treatment
1 finding from 1 review
Intervention not reported
LBW (< 2500 g) ‐ Treatment versus No Treatment · women with known obstetric outcomes
It is very uncertain whether the intervention changes LBW (< 2500 g) ‐ Treatment versus No Treatment (very low certainty).
1 finding from 1 review
Intervention not reported
NICU Admission ‐ Treatment versus No Treatment · women with known obstetric outcomes
The intervention may leads to higher NICU Admission ‐ Treatment versus No Treatment (low certainty).
1 finding from 1 review
Intervention not reported
Perinatal Mortality ‐ Treatment versus No Treatment · women with known obstetric outcomes
The intervention may leads to higher perinatal Mortality ‐ Treatment versus No Treatment (low certainty).
1 finding from 1 review