Mortality before hospital discharge · respiratory failure in preterm infants
Inhaled NO showed no clear difference in death before discharge ‐ Studies with entry before 3 days based on… compared with control (high certainty).
2 findings from 1 review
Neurodevelopmental disability · respiratory failure in preterm infants
Inhaled NO showed no clear difference in neurodevelopmental disability ‐ Studies with entry after 3 days… compared with control (moderate certainty).
2 findings from 1 review
Death or bronchopulmonary dysplasia · respiratory failure in preterm infants
Inhaled NO showed no clear difference in death or bronchopulmonary dysplasia at 36 weeks ‐ Studies with entry… compared with control (high certainty).
1 finding from 1 review
Death or bronchopulmonary dysplasia at 36 weeks PMA · respiratory failure in preterm infants
Inhaled NO showed no clear difference in death or bronchopulmonary dysplasia at 36 weeks ‐ Studies with entry… compared with control (high certainty).
1 finding from 1 review
Intraventricular haemorrhage, Papile grade 3/4 · respiratory failure in preterm infants
Inhaled NO showed no clear difference in intraventricular haemorrhage (grade 3 or 4) ‐ Studies with entry… compared with control (high certainty).
1 finding from 1 review
Intervention not reported
Length of NICU stay (days) · neonates requiring intubation and ventilation
1 finding from 1 review
Intervention not reported
Poor neurological outcome by 28 days' postnatal age · neonates requiring intubation and ventilation
The intervention showed no clear difference in poor neurological outcome by 28 days' postnatal age (moderate certainty).
1 finding from 1 review
Intervention not reported
Poor neurological outcome by 28 days' postnatal age · neonates requiring intubation and ventilation
The intervention probably leads to higher poor neurological outcome by 28 days' postnatal age (moderate certainty).
1 finding from 1 review
Intervention not reported
BPD at 28 days · Preterm neonates with respiratory distress
The intervention showed no clear difference in BPD at 28 days (low certainty).
1 finding from 1 review
Death or BPD (28 days) · preterm infants with respiratory distress for initial respiratory support
Inhaled steroids showed no clear difference in death or BPD at 28 days compared with systemic corticosteroids (low certainty).
1 finding from 1 review
BPD at 28 days · preterm infants with respiratory distress for initial respiratory support
Inhaled steroids showed no clear difference in BPD at 28 days compared with systemic corticosteroids (low certainty).
1 finding from 1 review
Intervention not reported
Duration of mechanical ventilation (days) · Preterm neonates with respiratory distress
1 finding from 1 review
Intervention not reported
Duration of supplemental oxygen (days) · Preterm neonates with respiratory distress
1 finding from 1 review
Intervention not reported
Mortality or CLD at 28/30 days · preterm infants
The intervention showed no clear difference in mortality or CLD at 28/30 days (low certainty).
1 finding from 1 review
Intervention not reported
Mortality to 28 days · preterm infants
It is very uncertain whether the intervention changes mortality to 28 days (very low certainty).
1 finding from 1 review
Intervention not reported
CLD at 28 days · preterm infants
The intervention showed no clear difference in CLD at 28 days (low certainty).
1 finding from 1 review
Intervention not reported
CLD among survivors to 28 days · preterm infants
The intervention showed no clear difference in CLD among survivors to 28 days (low certainty).
1 finding from 1 review
Intervention not reported
Days on mechanical ventilation · preterm infants
1 finding from 1 review
Number of episodes of regurgitation or vomiting per day · Formula‐fed healthy term infants up to 6 months of age with gastro‐oesophageal reflux
1 finding from 1 review
BPD at 28 days · neonates up to 44 weeks' postmenstrual age
Volume‐targeted showed no clear difference in BPD (supplemental oxygen at 28 days) compared with pressure‐limited ventilation: additional findings (low certainty).
1 finding from 1 review