Intervention not reported
Dental caries (presence; primary or permanent dentition)
The intervention led to higher dental caries (presence; primary or permanent dentition); GRADE not reported.
1 finding from 1 review
OR 1.50 [1.36, 1.64]
21 studies
GRADE not reported
Caries increment, surface index D(M)FS · Children or adolescents
In the illustrative network meta-regression the SMD for caries increment showed a treatment-by-year interaction and differed between fluoride in varnish and placebo at randomization years 1954 to 1980; certainty was not graded.
1 finding from 1 review
Proportion of dentists selecting selective or stepwise removal · Dentists surveyed about deep carious lesions in permanent teeth
In Oen 2007, 18% of surveyed dentists selected selective or stepwise removal.
12 findings from 1 review
Proportion (%) 18 [11, 27]
1 study · 85 participants
GRADE not reported
Proportion (%) 21 [12, 34]
1 study · 53 participants
GRADE not reported
Proportion (%) 62 [55, 69]
1 study · 171 participants
GRADE not reported
Show 9 more findings
Proportion (%) 71 [65, 77]
1 study · 252 participants
GRADE not reported
Proportion (%) 99 [95, 100]
1 study · 199 participants
GRADE not reported
Understanding dentists' management of deep carious lesions in permanent teeth: a systematic review and meta-analysis. 2016 All outcomesUnited States · Seale and Glickman 2007 (all 376 conference dentists; source mislabels as 'endodontists', but only 102 were endodontists)
Proportion (%) 59 [54, 64]
1 study · 376 participants
GRADE not reported
Proportion (%) 51 [44, 58]
1 study · 212 participants
GRADE not reported
Proportion (%) 68 [64, 71]
1 study · 622 participants
GRADE not reported
Proportion (%) 50 [47, 53]
1 study · 799 participants
GRADE not reported
Proportion (%) 35 [32, 38]
1 study · 812 participants
GRADE not reported
Proportion (%) 45 [26, 55]
1 study · 108 participants
GRADE not reported
Proportion (%) 49 [45, 52]
1 study · 661 participants
GRADE not reported
Intervention not reported
Dental caries prevalence in primary teeth (cavitated lesions) · Children aged 5-6 years in Latin America and the Caribbean
In other Latin American/Caribbean countries, pooled primary-teeth caries prevalence was 70% (95% CI 59-79%), significantly higher than Brazil (p=0.002); certainty not graded.
1 finding from 1 review
Intervention not reported
Dental caries prevalence in permanent teeth (cavitated lesions) · Children aged 11-13 years in Latin America and the Caribbean
In other Latin American/Caribbean countries, pooled permanent-teeth caries prevalence was 64% (95% CI 45-79%), not significantly different from Brazil (p=0.42); certainty not graded.
1 finding from 1 review
Proportion of dentists utilizing SE/SW for deep carious lesions · Dentists managing deep carious lesions in permanent vital teeth
Across nine surveys of 4199 dentists, a pooled 53% (95% CI 44% to 62%) chose selective or stepwise (evidence-based) carious tissue removal for deep lesions in permanent teeth, with very high heterogeneity (I2=96%) and no formal certainty rating (ungraded).
1 finding from 1 review
Intervention not reported
Dental caries prevalence in primary teeth (cavitated lesions) · Children aged 5-6 years in Latin America and the Caribbean
In Brazil, pooled primary-teeth caries prevalence in 5-6 year-olds was 52% (95% CI 49-54%); certainty not graded.
1 finding from 1 review
Intervention not reported
Dental caries prevalence in primary teeth (cavitated lesions) · Children aged 5-6 years in Latin America and the Caribbean
About 56% of 5-6 year-old children in Latin America and the Caribbean had dental caries in primary teeth (95% CI 52-59%); certainty not graded.
1 finding from 1 review
Intervention not reported
Dental caries prevalence in permanent teeth (cavitated lesions) · Children aged 11-13 years in Latin America and the Caribbean
In Brazil, pooled permanent-teeth caries prevalence in 11-13 year-olds was 56% (95% CI 53-60%), with a significant declining trend over time; certainty not graded.
1 finding from 1 review
Barriers and facilitators of SE/SW utilization · Dentists managing deep carious lesions in permanent vital teeth
Dentists' use of selective or stepwise removal was shaped by their age and understanding of caries, professional guidelines, peers and professional identity, financial and regulatory incentives, and beliefs about how treatments perform, identified by thematic analysis mapped to the TDF and Behavior Change Wheel (ungraded).
1 finding from 1 review
Thematic analysis mapped to the Theoretical Domains Framework and COM-B/Behavior Change Wheel; factors span knowledge (dentists' age, understanding of caries), skills, social influence (peers, practice networks),…
9 studies
GRADE not reported
Temporal change in the proportion of dentists utilizing SE/SW · Dentists managing deep carious lesions in permanent vital teeth
The proportion of dentists choosing selective or stepwise removal rose significantly over time, by about 1.6% per calendar year (meta-regression, p<0.05), a trend the authors described as borderline (ungraded).
1 finding from 1 review
Intervention not reported
Dental caries prevalence in permanent teeth (cavitated lesions) · Children aged 11-13 years in Latin America and the Caribbean
About 58% of 11-13 year-old children in Latin America and the Caribbean had dental caries in permanent teeth (95% CI 54-61%); certainty not graded.
1 finding from 1 review
Mean DMFT (decayed, missing, filled permanent teeth) · Individuals of all ages
Individuals with Down syndrome had a lower mean DMFT in permanent teeth than controls (pooled SMD -0.18, 95% CI -0.35 to -0.02; 6 studies; I2=20%); certainty of evidence not graded.
1 finding from 1 review
Dental caries · Children with exclusively primary dentition (age ≤71 months)
In a meta-analysis of two cross-sectional studies, breastfed children had lower odds of dental caries than bottle-fed children (OR 0.43, 95% CI 0.23 to 0.80); certainty was not formally graded.
2 findings from 1 review
OR 0.43 [0.23, 0.80]
2 studies · 620 participants
GRADE not reported
Breast and Bottle Feeding as Risk Factors for Dental Caries: A Systematic Review and Meta-Analysis. 2015 All outcomesKindergartens, hospitals and health centres; Kuwait, China, Syria, Sri Lanka, South Africa and Italy
Four studies showed that bottle fed children had more dental caries (p<0.05), while three studies found no such association (p>0.05); the review concluded that breastfeeding can protect against dental caries in early…
7 studies
GRADE not reported
Dental caries · Individuals of all ages
Individuals with Down syndrome had a lower prevalence of dental caries than those without (pooled OR 0.36, 95% CI 0.22 to 0.57; 2 studies; I2=0%); certainty of evidence not graded.
1 finding from 1 review
Prostate cancer · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for Prostate cancer: OR 1.04 (95% CI 0.98 to 1.09), not statistically significant. Umbrella review outcome-level evidence grade: Substantial effect unlikely.
1 finding from 1 review
Alzheimer’s disease · Participants in observational studies
The meta-analysis of observational studies reported a SMD (to OR) of 0.08 (95% CI 0.01 to 0.63) for higher versus lower circulating vitamin D concentration.
1 finding from 1 review
Aggressive prostate cancer · Participants in observational studies
The meta-analysis of observational studies reported a OR of 0.88 (95% CI 0.68 to 1.15) for higher versus lower circulating vitamin D concentration.
1 finding from 1 review
Fasting blood glucose (mg/dL) · Adults with diabetes
Meta-analysis of randomised trials of vitamin D supplementation for Fasting glucose (Diabetes patients with normal glucose tolerance): WMD 0.01 (95% CI -0.21 to 0.23), not statistically significant. Umbrella review outcome-level evidence grade: Substantial effect unlikely.
2 findings from 1 review
WMD 0.01 [-0.21, 0.23]
Studies not reported
GRADE not reported
WMD -0.3 [-0.9, 0.3]
Studies not reported
GRADE not reported
Economic factors · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage
The review found no eligible studies for this question.
1 finding from 1 review