Progression of non-cavitated enamel caries · Children with caries-free second primary molars, aged 4-8 years (dental clinic, Turkey and Spain)
The review found no eligible studies for this question.
1 finding from 1 review
Association between age and daily fluoride intake from toothpaste · Children using fluoride toothpaste (all tap-water fluoride categories)
There was no correlation between daily fluoride intake from toothpaste and the age of children (all R2 < 0.14), across all tap-water fluoride categories (ungraded).
1 finding from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
3 findings from 1 review
Bay 1993 compared essential oil mouthwash C (Listerine) with distilled water and reported combined CFUs at different levels using Andersen's air sampler; level 2 (pharynx) was considered patient level and was not…
1 study
GRADE not reported
At operator level, because of high heterogeneity (I2 = 98%), the results were not meta-analysed (3 studies; Gupta 2014, Nayak 2020, Shetty 2013). No pooled estimate or GRADE rating.
3 studies
GRADE not reported
At assistant level, because of high heterogeneity (I2 = 99%), the results were not meta-analysed (3 studies; Gupta 2014, Nayak 2020, Shetty 2013). No pooled estimate or GRADE rating.
3 studies
GRADE not reported
Pain · Adults (>18 years) with established dry socket following permanent tooth extraction
1 finding from 1 review
Duration of treatment (days) · Adults (>18 years) with established dry socket following permanent tooth extraction
Metronidazole (intrasocket) led to lower duration of treatment (days) compared with placebo; GRADE not reported.
1 finding from 1 review
Restoration survival · Children with occlusoproximal caries in primary teeth
Multiple reviews reported similar restoration survival for ART versus conventional restorations in occlusoproximal cavities (ungraded).
1 finding from 1 review
Gingivitis · School children (aged 4 to 15 years), primary and secondary schools in the UK and India
The review found no eligible studies for this question.
1 finding from 1 review
Dental caries (association with middle SES) · Children (deciduous and/or permanent dentition) in low- and middle-income countries
Middle SES showed no significant association with dental caries (OR 0.80, 95% CI 0.59 to 1.10; 7 studies; not GRADE-rated).
1 finding from 1 review
Contribution to total daily fluoride intake · children
For children in high-fluoridated areas, the mean contribution was 41% (SD 24%).
1 finding from 1 review
Mucocele · Children or adolescents
No significant difference in mucocele between groups (OR 3.03, 95% CI 0.12 to 75.37; single study).
1 finding from 1 review
Adverse events · Children with sound primary molars, aged 2-4 years (municipal dental clinics or hospital paediatric clinics, Denmark)
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · Children who were regular dental attenders with caries-free first or second primary molars (public health service clinic, Brazil)
The review found no eligible studies for this question.
1 finding from 1 review
Immediate bond strength (MPa) · Glass-ionomer cement bonded to caries-affected dentin (in vitro)
SDF pretreatment with a rinsing step does not affect glass-ionomer cement bond strength to caries-affected dentin (MD -0.36 MPa, 95% CI -1.07 to 0.35; ungraded).
1 finding from 1 review
Immediate bond strength (MPa) · Glass-ionomer cement bonded to dentin (in vitro), sound or caries-affected
Prior SDF application does not influence the immediate bond strength of glass-ionomer cement to dentin (MD -0.11 MPa, 95% CI -0.54 to 0.31; ungraded).
1 finding from 1 review
Treatment failure (annual failure rate) · Children with carious primary teeth treated by atraumatic restorative treatment (hand-instrument caries removal), no pulp therapy
ART restorations (mainly GIC) had a wide annual failure rate (1.2-37.1%) across 10 RCTs, with technique affecting survival; low to unclear quality of evidence (ungraded).
1 finding from 1 review
Caries experience at the surface level (dmfs/defs) · Children (mean age newborn to ~5.2 years) and their parents/carers
Behaviour change interventions delivered by non-dental health workers produced a small, statistically significant reduction in caries experience at the surface level (dmfs SMD -0.15, 95% CI -0.25 to -0.04; 12 studies); the review judged the overall evidence to be of low quality (not GRADE-rated).
1 finding from 1 review
Complications and side effects · People treated with oral bisphosphonates undergoing dental extractions (at risk of MRONJ)
1 finding from 1 review
Alpha diversity (Shannon) · Children providing oral (saliva/supragingival plaque) 16S rRNA microbiome samples
In children, caries-vs-health Shannon alpha diversity differed significantly (ungraded).
1 finding from 1 review
Dentinal caries in permanent (newly erupted) teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)
Dentinal caries in the primary dentition is associated with about 3.2 times higher odds of dentinal caries in permanent teeth (single study; not GRADE-rated).
1 finding from 1 review
Discrimination of caries vs health (random forest ROC-AUC) · Individuals providing oral (saliva/supragingival plaque) 16S rRNA microbiome samples; 2016 samples from 19 studies (mixed children and…
Microbiome-based random forest classifiers could not reliably discriminate caries from health across the combined cohort (best AUC approximately 0.75 in a disease-only KO subset; ungraded).
1 finding from 1 review