Total mortality · people with primary hypertension
All angiotensin converting enzyme (ACE) inhibitors showed no clear difference in total mortality compared with all angiotensin receptor blockers (ARBs) (moderate certainty).
1 finding from 1 review
Total mortality · adults with primary hypertension
First‐line angiotensin converting enzyme inhibitor probably leads to lower total mortality compared with placebo (moderate certainty).
1 finding from 1 review
Total mortality Mean duration of 3.8 years · adults 60 years or older with primary hypertension
Antihypertensive drug leads to lower total mortality Mean duration of 3.8 years compared with placebo or no treatment (high certainty).
1 finding from 1 review
Cardiovascular mortality and morbidity Mean duration of 3.7 years · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)
Antihypertensive drug therapy may leads to lower total cardiovascular mortality + morbidity compared with control (low certainty).
1 finding from 1 review
Total mortality · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…
Aspirin showed no clear difference in total mortality compared with placebo (low certainty).
1 finding from 1 review
Total mortality · Men and non‐pregnant women ≥ 18 years old with essential hypertension
1 finding from 1 review
Total mortality · Men and non‐pregnant women ≥ 18 years old with essential hypertension
Naltrexone/bupropion showed no clear difference in total mortality compared with placebo (moderate certainty).
1 finding from 1 review
Total mortality · Men and non‐pregnant women ≥ 18 years old with essential hypertension
1 finding from 1 review
Total mortality · Men and non‐pregnant women ≥ 18 years old with essential hypertension
1 finding from 1 review
Total mortality · adult patients with hypertension
Lower BP target showed no clear difference in total mortality compared with standard BP target (high certainty).
1 finding from 1 review
RR 0.95 [0.86, 1.05]
Studies not reported
High
Total mortality · people with primary hypertension
It is very uncertain whether combination therapy changes total mortality compared with monotherapy (very low certainty).
1 finding from 1 review
Total mortality · people with primary hypertension
It is very uncertain whether combination with potassium‐sparing diuretics changes total mortality compared with monotherapy (very low certainty).
1 finding from 1 review
Total mortality · adults with primary hypertension
1 finding from 1 review
Total mortality · adults with primary hypertension
First‐line beta‐blocker showed no clear difference in total mortality compared with placebo (moderate certainty).
1 finding from 1 review
Total mortality · adults with primary hypertension
First‐line calcium channel blocker showed no clear difference in total mortality compared with placebo (low certainty).
1 finding from 1 review
Total mortality · adults with primary hypertension
1 finding from 1 review
Total mortality
Beta‐blockers showed no clear difference in total mortality compared with renin‐angiotensin system inhibitors (moderate certainty).
1 finding from 1 review
Total mortality Duration: 3.2 years · patients with hypertension
First‐line thiazides showed no clear difference in total mortality Duration: 3.2 years compared with first‐line alpha‐blockers (moderate certainty).
1 finding from 1 review
Total mortality Duration: 1 to 5 years · patients with hypertension
First‐line thiazides showed no clear difference in total mortality Duration: 1 to 5 years compared with first‐line ACE inhibitors (moderate certainty).
1 finding from 1 review
Total mortality Duration: 1 to 5 years · patients with hypertension
First‐line thiazides showed no clear difference in total mortality Duration: 1 to 5 years compared with first‐line calcium channel blockers (moderate certainty).
1 finding from 1 review